Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6943807 | 1.00 | HTT (0.50) | HTTCTSKSMN1; SMN2LMNASLC1A3 | |
| SCHEMBL6404796 | 0.89 | HTT (0.59) | HTTCTSKSMN1; SMN2LMNACTSS | |
| SCHEMBL6940690 | 0.89 | HTT (0.59) | HTTCTSKSMN1; SMN2LMNACTSS | |
| SCHEMBL2722875 | 0.86 | LMNA (0.51) | HTTCTSKSMN1; SMN2LMNASLC1A3 | |
| SCHEMBL16828854 | 0.86 | PSMB1 (0.53) | HTTCTSKSMN1; SMN2LMNASLC1A3 | |
| SCHEMBL7533308 | 0.86 | LMNA (0.51) | HTTCTSKSMN1; SMN2LMNASLC1A3 | |
| SCHEMBL7535276 | 0.86 | LMNA (0.51) | HTTCTSKSMN1; SMN2LMNASLC1A3 | |
| SCHEMBL2723527 | 0.85 | LMNA (0.52) | HTTCTSKSMN1; SMN2LMNASLC1A3 | |
| SCHEMBL18086889 | 0.85 | CTSK (0.55) | HTTCTSKSMN1; SMN2LMNACTSS | |
| SCHEMBL6943800 | 0.85 | HSD17B10 (0.50) | HTTCTSKSMN1; SMN2LMNACTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |