Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA7 | P43166 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5893589 | 0.79 | CA12 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28506010 | 0.77 | F2 (0.45) | HPGDALDH1A1HSD17B10POLBTDP1 | |
| SCHEMBL8319149 | 0.71 | TSHR (0.37) | HPGDALDH1A1HSD17B10POLBKMT2A | |
| SCHEMBL28702972 | 0.70 | TSHR (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8993267 | 0.67 | ALDH1A1 (0.53) | CA12CA1CA2CA9HPGD | |
| SCHEMBL5875331 | 0.67 | SERPINE1 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28276553 | 0.66 | CA12 (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL12432928 | 0.65 | HPGD (0.33) | HPGD | |
| SCHEMBL5893722 | 0.65 | NPC1 (0.46) | CA12CA1CA2CA9HPGD | |
| SCHEMBL5874975 | 0.64 | POLB (0.46) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183248-B1 | NON-LINEAR OPTICAL DEVICES AND MATERIALS THEREFOR | QINETIQ LTD (GB) | 2003-06-18 | — | — | EP | disclosed |
| EP-1183248-A1 | NON-LINEAR OPTICAL DEVICES AND MATERIALS THEREFOR | QinetiQ Limited (GB) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000068217-A1 | NON-LINEAR OPTICAL DEVICES AND MATERIALS THEREFOR | QINETIQ LIMITED (GB) | 2000-11-16 | — | — | WO | disclosed |