Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31226298 | 0.81 | TSHR (0.38) | TSHREPHX2 | |
| SCHEMBL457124 | 0.77 | SIGMAR1 (0.33) | TSHREPHX2 | |
| SCHEMBL18652968 | 0.71 | — | — | |
| SCHEMBL733849 | 0.71 | GRIN1 (0.48) | TSHREPHX2 | |
| SCHEMBL3190483 | 0.71 | GRIN1 (0.48) | TSHREPHX2 | |
| Bromide SCHEMBL4732099 | 0.69 | GRIN1 (0.46) | TSHREPHX2 | |
| Methyl Alcohol SCHEMBL28225130 | 0.67 | TSHR (0.48) | TSHREPHX2 | |
| Dimethylamine SCHEMBL4774387 | 0.65 | GRIN1 (0.50) | TSHREPHX2 | |
| SCHEMBL7529469 | 0.64 | APLNR (0.33) | — | |
| SCHEMBL540055 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0928788-B1 | Imidazolidin-4-one derivatives useful as anticancer agents | PFIZER PROD INC (US) | 2003-02-12 | — | — | EP | disclosed |
| US-6174903-B1 | INHIBITORS OF THE ENZYME FARNESYL PROTEIN TRANSFERASE AND ARE THEREFORE CAN BE USED AS ANTICANCER AGENT AND ANTITUMOR AGENT | PFIZER INC. | 2001-01-16 | — | — | US | disclosed |
| US-6080769-A | Imidazolidin-4-one derivatives useful as anticancer agents | PFIZER INC. (US) | 2000-06-27 | — | — | US | disclosed |
| EP-0928788-A1 | Imidazolidin-4-one derivatives useful as anticancer agents | Pfizer Products Inc. (US) | 1999-07-14 | — | — | EP | disclosed |