Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 3/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.45 |
| ▸ | REN | P00797 | 8/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941201 | 1.00 | PPARA (0.45) | PPARAPPARGLDHAPDE4APDE4B | |
| SCHEMBL6948739 | 0.88 | MTNR1A (0.50) | PPARGREN | |
| SCHEMBL6948737 | 0.88 | MTNR1A (0.50) | PPARGREN | |
| SCHEMBL6943609 | 0.83 | PPARA (0.56) | PPARAPPARGPDE4APDE4BPDE4C | |
| SCHEMBL17768390 | 0.82 | REN (0.49) | PPARAPPARGPDE4APDE4BPDE4C | |
| SCHEMBL14538389 | 0.82 | PPARA (0.57) | PPARAPPARGPDE4APDE4BPDE4C | |
| SCHEMBL6942961 | 0.81 | REN (0.44) | PPARAPPARGPDE4APDE4BPDE4C | |
| SCHEMBL6942964 | 0.81 | REN (0.44) | PPARAPPARGPDE4APDE4BPDE4C | |
| SCHEMBL6943259 | 0.81 | REN (0.43) | PPARAPPARGPDE4APDE4BPDE4C | |
| SCHEMBL27930278 | 0.80 | STAT3 (0.45) | LDHARENSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |