Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 7/20 | 0.44 |
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942961 | 1.00 | REN (0.44) | RENPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6947411 | 0.87 | SIGMAR1 (0.54) | SIGMAR1PPARAPPARG | |
| SCHEMBL6947408 | 0.87 | SIGMAR1 (0.54) | SIGMAR1PPARAPPARG | |
| SCHEMBL6940727 | 0.83 | MTNR1A (0.54) | PDE4APDE4BPDE4CPDE4DSIGMAR1 | |
| SCHEMBL6940732 | 0.83 | MTNR1A (0.54) | PDE4APDE4BPDE4CPDE4DSIGMAR1 | |
| SCHEMBL7076864 | 0.82 | PPARA (0.42) | PDE4APDE4BPDE4CPDE4DSIGMAR1 | |
| SCHEMBL7076862 | 0.82 | PPARA (0.42) | PDE4APDE4BPDE4CPDE4DSIGMAR1 | |
| SCHEMBL6941201 | 0.81 | PPARA (0.45) | RENPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6941202 | 0.81 | PPARA (0.45) | RENPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6940652 | 0.80 | TUBB4A (0.54) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |