Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.44 |
| ▸ | RAF1 | P04049 | 3/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6948739 | 1.00 | MTNR1A (0.50) | MTNR1AMTNR1BAPPPTGESALOX5 | |
| SCHEMBL6941202 | 0.88 | PPARA (0.45) | PPARGREN | |
| SCHEMBL6941201 | 0.88 | PPARA (0.45) | PPARGREN | |
| SCHEMBL6943578 | 0.81 | MTNR1A (0.46) | MTNR1AMTNR1BAPPPTGESALOX5 | |
| SCHEMBL11034611 | 0.80 | MTNR1A (0.51) | MTNR1AMTNR1BAPPFFAR4C5AR1 | |
| SCHEMBL20576388 | 0.79 | MTNR1A (0.47) | MTNR1AMTNR1BAPPPTGESALOX5 | |
| SCHEMBL6940727 | 0.79 | MTNR1A (0.54) | MTNR1AMTNR1BAPPHDAC1KDM4E | |
| SCHEMBL6940732 | 0.79 | MTNR1A (0.54) | MTNR1AMTNR1BAPPHDAC1KDM4E | |
| SCHEMBL13131318 | 0.78 | APP (0.48) | MTNR1AMTNR1BAPPC5AR1KDM4E | |
| SCHEMBL6044557 | 0.77 | MTNR1A (0.47) | MTNR1AMTNR1BAPPC5AR1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |