Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | ADA | P00813 | 6/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935843 | 0.83 | KMO (0.40) | KMOADAP2RX7LMNAGAA | |
| SCHEMBL6938261 | 0.82 | LMNA (0.45) | ADALMNA | |
| SCHEMBL6942807 | 0.76 | L3MBTL1 (0.44) | CYP1A2SMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL6170042 | 0.76 | ADA (0.54) | ADAMEN1 | |
| SCHEMBL6941436 | 0.76 | ADA (0.60) | KMOADA | |
| SCHEMBL5673950 | 0.76 | ADA (0.45) | ADALMNAPOLB | |
| SCHEMBL6171815 | 0.75 | ADA (0.46) | ADACYP1A2POLB | |
| SCHEMBL6133548 | 0.75 | ADA (0.61) | ADANPC1RAB9APOLB | |
| SCHEMBL6168401 | 0.75 | ADA (0.59) | ADALMNAMEN1KMT2A | |
| SCHEMBL6173074 | 0.75 | ADA (0.53) | ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596738-B1 | Inhibiting activity to adenosine deaminase (hereinafter described as ADA) An adenosine deaminase inhibiting agent comprising a compound of the formula (I): | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-22 | — | — | US | disclosed |