Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 11/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6943202 | 0.88 | REN (0.55) | RENLMNATSHRKDM4ESLC5A7 | |
| Hydrochloric Acid SCHEMBL6947328 | 0.88 | REN (0.57) | RENLMNATSHRKDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL6942968 | 0.88 | REN (0.56) | RENKDM4EALDH1A1GLAMAPT | |
| SCHEMBL6940726 | 0.82 | REN (0.52) | RENLMNATSHRKDM4EALDH1A1 | |
| SCHEMBL6943818 | 0.82 | REN (0.43) | RENTDP1MEN1KMT2AHTT | |
| SCHEMBL6944413 | 0.82 | REN (0.48) | RENLMNATSHRKDM4EALDH1A1 | |
| SCHEMBL6943661 | 0.82 | LMNA (0.47) | RENLMNATSHRKDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL6938981 | 0.81 | REN (0.53) | RENLMNATSHRKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6947174 | 0.81 | REN (0.44) | RENMEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL6947816 | 0.81 | REN (0.49) | RENLMNATSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |