Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.56 |
| ▸ | GAA | P10253 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | THRB | P10828 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23486316 | 0.72 | MAPT (0.64) | MAPTGAAKDM4EKMT2ATHRB | |
| SCHEMBL525918 | 0.72 | LMNA (0.65) | KDM4ETSHRALDH1A1TDP1HTT | |
| SCHEMBL447639 | 0.72 | LMNA (0.65) | KDM4ETSHRALDH1A1TDP1HTT | |
| SCHEMBL3171676 | 0.72 | LMNA (0.65) | KDM4ETSHRALDH1A1TDP1HTT | |
| SCHEMBL29990536 | 0.72 | LMNA (0.65) | KDM4ETSHRALDH1A1TDP1HTT | |
| SCHEMBL700288 | 0.72 | MAPT (0.62) | MAPTGAAKDM4EKMT2ATHRB | |
| SCHEMBL14514123 | 0.71 | LMNA (0.56) | KDM4ETSHRALDH1A1TDP1POLB | |
| SCHEMBL16600651 | 0.70 | MAPT (0.68) | MAPTGAAKDM4EKMT2ATHRB | |
| SCHEMBL9302694 | 0.70 | LMNA (0.62) | KDM4ETSHRALDH1A1TDP1HTT | |
| Ammonia Solution, Strong SCHEMBL10589724 | 0.70 | LMNA (0.62) | KDM4ETSHRALDH1A1TDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421613-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND A CHELANT AND USE THEREOF | The Procter & Gamble Company (US) | 2012-02-29 | — | — | EP | claimed |
| US-7985266-B2 | Keratin dyeing compositions comprising a radical scavenger and a chelant and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2011-07-26 | — | — | US | claimed |
| US-20110035886-A1 | Keratin Dyeing Compositions Comprising a Radical Scavenger and a Chelant and Use Thereof | NOXELL CORPORATION | 2011-02-17 | — | — | US | claimed |
| WO-2010123866-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND A CHELANT AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2010-10-28 | — | — | WO | claimed |
| EP-2421613-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND A CHELANT AND USE THEREOF | The Procter & Gamble Company (US) | 2012-02-29 | — | — | EP | disclosed |
| US-7985266-B2 | Keratin dyeing compositions comprising a radical scavenger and a chelant and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2011-07-26 | — | — | US | disclosed |
| US-20110035886-A1 | Keratin Dyeing Compositions Comprising a Radical Scavenger and a Chelant and Use Thereof | NOXELL CORPORATION | 2011-02-17 | — | — | US | disclosed |
| WO-2010123866-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND A CHELANT AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2010-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110035886-A1 | Keratin Dyeing Compositions Comprising a Radical Scavenger and a Chelant and Use Thereof | KRT18, LPO, KRTCAP2 | MAPT 547/4885GAA 1970/4885KDM4E 509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.