Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.32 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2132123 | 1.00 | FOLH1 (0.32) | FOLH1RIMKLANAALAD2KDRENPEP | |
| SCHEMBL142363 | 0.83 | GGT1 (0.36) | FOLH1RIMKLANAALAD2ENPEPTGFBR1 | |
| SCHEMBL142364 | 0.83 | GGT1 (0.36) | FOLH1RIMKLANAALAD2ENPEPTGFBR1 | |
| SCHEMBL8330610 | 0.75 | LMNA (0.36) | SLC22A6 | |
| SCHEMBL8358625 | 0.75 | FOLH1 (0.43) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL31515380 | 0.75 | TGFBR1 (0.31) | ENPEPTGFBR1 | |
| SCHEMBL9686357 | 0.75 | ECE1 (0.40) | ENPEP | |
| SCHEMBL26693279 | 0.75 | TGFBR1 (0.31) | ENPEPTGFBR1 | |
| SCHEMBL13213154 | 0.74 | SLC22A6 (0.38) | FOLH1RIMKLANAALAD2ENPEPTGFBR1 | |
| SCHEMBL3661989 | 0.74 | SLC22A6 (0.38) | FOLH1RIMKLANAALAD2ENPEPTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1276716-A2 | METAL CHELATING COMPOSITIONS | Sigma-Aldrich Company (US) | 2003-01-22 | — | — | EP | disclosed |
| WO-2001081365-A2 | METAL CHELATING COMPOSITIONS | SIGMA-ALDRICH CO. (US) | 2001-11-01 | — | — | WO | disclosed |