SCHEMBL142364

SCHEMBL142364

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nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GGT1 P19440 1/20 0.36
TGFBR1 P36897 3/20 0.33
ENPEP Q07075 2/20 0.33
SLC22A6 Q4U2R8 1/20 0.33
FOLH1 Q04609 1/20 0.30
RIMKLA Q8IXN7 1/20 0.30
NAALAD2 Q9Y3Q0 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MAPT P10636 1/20 0.30
THRB P10828 1/20 0.30
ALOX15 P16050 1/20 0.30
NFKB1 P19838 1/20 0.30
PTGS2 P35354 1/20 0.30
THPO P40225 1/20 0.30
RECQL P46063 1/20 0.30
BLM P54132 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL142363 1.00 GGT1 (0.36) GGT1TGFBR1ENPEPSLC22A6FOLH1
SCHEMBL28418756 0.85 NOD1 (0.45) SMN1; SMN2
SCHEMBL7105130 0.83 FNTA (0.34) GGT1ENPEP
SCHEMBL7105125 0.83 FNTA (0.34) GGT1ENPEP
SCHEMBL2132123 0.83 FOLH1 (0.32) TGFBR1ENPEPSLC22A6FOLH1RIMKLA
SCHEMBL6943387 0.83 FOLH1 (0.32) TGFBR1ENPEPSLC22A6FOLH1RIMKLA
SCHEMBL9686357 0.78 ECE1 (0.40) ENPEP
SCHEMBL31515380 0.78 TGFBR1 (0.31) TGFBR1ENPEPMAPTSMN1; SMN2
SCHEMBL26693279 0.78 TGFBR1 (0.31) TGFBR1ENPEPMAPTSMN1; SMN2
SCHEMBL3661989 0.77 SLC22A6 (0.38) TGFBR1ENPEPSLC22A6FOLH1RIMKLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 408 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11628127-B2 Composition for lightening or dyeing keratin fibers with a low amount of oxidizing agent WELLA OPERATIONS US, LLC (US) 2023-04-18 US claimed
US-20180049958-A1 AGENT FOR IMPROVED OXIDATIVE LIGHTENING OF KERATINIC FIBRES HENKEL AG & CO. KGAA (DE) 2018-02-22 US claimed
US-20160331664-A1 AGENTS FOR GENTLY OXIDATIVELY LIGHTENING KERATIN-CONTAINING FIBERS HENKEL AG & CO. KGAA (DE) 2016-11-17 US claimed
US-5686402-A ANTISOILANTS; REDUCED PHOSPHATE CONTENT LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1997-11-11 US claimed
WO-1997024322-A1 ETHYLENE DICYSTEATE SEQUESTRANTS AND DETERGENT COMPOSITIONS CONTAINING THEM UNILEVER PLC (GB) 1997-07-10 WO claimed
EP-4748455-A1 ANTI-GREY-HAIR COMPOSITION COMPRISING PLANT EXTRACTS Wella Germany GmbH (DE) 2026-05-27 EP disclosed
EP-4748454-A1 ANTI-GREY-HAIR COMPOSITION Wella Germany GmbH (DE) 2026-05-27 EP disclosed
US-20260137750-A1 ANTI-GREY-HAIR COMPOSITION WELLA GERMANY GMBH (DE) 2026-05-21 US disclosed
US-12622856-B2 Agent for oxidative dyeing of keratin fibers, containing isatin and at least one defined polymer HENKEL AG & CO. KGAA (DE) 2026-05-12 US disclosed
EP-4729046-A2 COMPOSITIONS HAVING ENHANCED DEPOSITION OF SURFACTANT SOLUBLE ANTIDANDRUFF AGENTS The Procter & Gamble Company (US) 2026-04-22 EP disclosed
EP-4719328-A1 BLEACHING MEDIUM COMPRISING A PHENALENONE Wella Germany GmbH (DE) 2026-04-08 EP disclosed
EP-4710913-A2 METHOD AND APPARATUS FOR DYEING HAIR FIBRES USING RADIO FREQUENCY ELECTROMAGNETIC RADIATION Jemella Limited (GB) 2026-03-18 EP disclosed
WO-2002089754-A1 COMPOSITIONS SUITABLE FOR THE TREATMENT OF HAIR COMPRISING CHELANTS AND METHODS FOR REDUCING OXIDATIVE HAIR DAMAGE THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO disclosed
WO-2002074272-A1 OXIDATIVE TREATMENT OF HAIR WITH REDUCED HAIR DAMAGE THE PROCTER & GAMBLE COMPANY (US) 2002-09-26 WO disclosed
WO-2002074273-A1 OXIDIZING COMPOSITIONS COMPRISING A CHELANT AND A CONDITIONING AGENT AND METHODS OF TREATING HAIR THE PROCTER & GAMBLE COMPANY (US) 2002-09-26 WO disclosed
WO-2002074271-A1 OXIDATIVE TREATMENT OF HAIR WITH REDUCED HAIR DAMAGE THE PROCTER & GAMBLE COMPANY (US) 2002-09-26 WO disclosed
US-5693854-A CHELANTS; BUILDERS FOR DETERGENTS LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. 1997-12-02 US disclosed
US-5686402-A ANTISOILANTS; REDUCED PHOSPHATE CONTENT LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1997-11-11 US disclosed
WO-1997024322-A1 ETHYLENE DICYSTEATE SEQUESTRANTS AND DETERGENT COMPOSITIONS CONTAINING THEM UNILEVER PLC (GB) 1997-07-10 WO disclosed
WO-1997024322-A1 ETHYLENE DICYSTEATE SEQUESTRANTS AND DETERGENT COMPOSITIONS CONTAINING THEM UNILEVER PLC (GB) 1997-07-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137750-A1 ANTI-GREY-HAIR COMPOSITION OAT, CUTA, NASP GGT1 990/4885TGFBR1 4082/4885ENPEP 1775/4885
US-12622856-B2 Agent for oxidative dyeing of keratin fibers, containing isatin and at least one defined polymer KRT18, ARSA, MKI67 GGT1 957/4885TGFBR1 1807/4885ENPEP 1107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.