Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | CDK8 | P49336 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6939723 | 0.83 | MAPT (0.58) | ALDH1A1NPSR1CDK8MEN1KMT2A | |
| SCHEMBL8103125 | 0.82 | P2RY1 (0.55) | ALDH1A1NPSR1MEN1KMT2ALMNA | |
| SCHEMBL7070334 | 0.80 | GAA (0.56) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL10710090 | 0.77 | MEN1 (0.79) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL6943393 | 0.77 | LPAR1 (0.67) | MEN1KMT2ALMNACA12CA1 | |
| SCHEMBL4865713 | 0.76 | ADRA2C (0.54) | ALDH1A1LMNAMAPTCA12CA1 | |
| SCHEMBL6943804 | 0.76 | P2RY1 (0.58) | MEN1KMT2AMAPTCA12CA1 | |
| SCHEMBL6826223 | 0.75 | MAOA (0.50) | ALDH1A1NPSR1MEN1KMT2AMAPT | |
| SCHEMBL31448129 | 0.75 | MAOA (0.50) | ALDH1A1NPSR1MEN1KMT2AMAPT | |
| SCHEMBL6937514 | 0.74 | MEN1 (0.65) | ALDH1A1NPSR1CDK8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042278-B1 | 1,3-DISUBSTITUTED UREAS AS ACAT INHIBITORS, AND METHOD OF PREPARING THEREOF | SLOVAKOFARMA AS (SK) | 2003-03-05 | — | — | EP | disclosed |
| US-6444691-B1 | ANTICHOLESTEROL AGENTS | SOLVAKOFARMA, A.S. (SK) | 2002-09-03 | — | — | US | disclosed |