Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 8/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6939932 | 0.84 | LPAR1 (0.62) | LPAR1LMNAL3MBTL1POLBKMT2A | |
| SCHEMBL7070334 | 0.84 | GAA (0.56) | LPAR1LMNAL3MBTL1CA12CA1 | |
| SCHEMBL6943396 | 0.77 | ALDH1A1 (0.61) | LMNAL3MBTL1CA12CA1CA2 | |
| SCHEMBL4865713 | 0.76 | ADRA2C (0.54) | LMNAL3MBTL1CA12CA1CA2 | |
| SCHEMBL7950202 | 0.74 | NCOA1 (0.51) | L3MBTL1POLBKMT2AMEN1 | |
| SCHEMBL462304 | 0.74 | LPAR1 (0.66) | LPAR1LMNAKMT2AMEN1 | |
| SCHEMBL6943804 | 0.73 | P2RY1 (0.58) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL8103125 | 0.72 | P2RY1 (0.55) | LMNAL3MBTL1CA12CA1CA2 | |
| SCHEMBL19538842 | 0.69 | L3MBTL1 (0.76) | LMNAL3MBTL1CA12CA1CA2 | |
| SCHEMBL9435674 | 0.69 | KMT2A (0.63) | LPAR1LMNAEPHX2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042278-B1 | 1,3-DISUBSTITUTED UREAS AS ACAT INHIBITORS, AND METHOD OF PREPARING THEREOF | SLOVAKOFARMA AS (SK) | 2003-03-05 | — | — | EP | disclosed |
| US-6444691-B1 | ANTICHOLESTEROL AGENTS | SOLVAKOFARMA, A.S. (SK) | 2002-09-03 | — | — | US | disclosed |
| EP-1042278-A1 | 1,3-DISUBSTITUTED UREAS AS ACAT INHIBITORS, AND METHOD OF PREPARING THEREOF | Slovakofarma, A.S. (SK) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999032437-A1 | 1,3-DISUBSTITUTED UREAS AS ACAT INHIBITORS, AND METHOD OF PREPARING THEREOF | SLOVAKOFARMA, A.S. (SK) | 1999-07-01 | — | — | WO | disclosed |