Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7081648 | 0.81 | L3MBTL1 (0.45) | L3MBTL1ACHELMNAGLS | |
| SCHEMBL6947604 | 0.79 | ERCC5 (0.61) | HAO1PTPN1ERCC5FEN1LMNA | |
| SCHEMBL6950010 | 0.76 | ALDH1A1 (0.50) | HAO1PTPN1GAASMN1; SMN2ERCC5 | |
| SCHEMBL7671810 | 0.75 | CYP19A1 (0.46) | HAO1PTPN1ERCC5FEN1 | |
| SCHEMBL596252 | 0.74 | L3MBTL1 (0.96) | L3MBTL1ACHEGAASMN1; SMN2HRH3 | |
| SCHEMBL7269112 | 0.72 | L3MBTL1 (1.00) | L3MBTL1ACHEGAASMN1; SMN2HRH3 | |
| SCHEMBL1626076 | 0.72 | L3MBTL1 (1.00) | L3MBTL1ACHEGAASMN1; SMN2HRH3 | |
| SCHEMBL9212361 | 0.72 | L3MBTL1 (1.00) | L3MBTL1ACHEGAASMN1; SMN2HRH3 | |
| SCHEMBL610772 | 0.72 | L3MBTL1 (1.00) | L3MBTL1ACHEGAASMN1; SMN2HRH3 | |
| Hydrochloric Acid SCHEMBL27853152 | 0.72 | L3MBTL1 (0.93) | L3MBTL1ACHEGAASMN1; SMN2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082121-A4 | HIV INTEGRASE INHIBITORS | MERCK & CO INC (US) | 2003-02-05 | — | — | EP | claimed |
| US-6380249-B1 | HIV integrase inhibitors | MERCK & CO., INC. | 2002-04-30 | — | — | US | claimed |
| EP-1082121-A1 | HIV INTEGRASE INHIBITORS | Merck & Co., Inc. (US) | 2001-03-14 | — | — | EP | claimed |
| WO-1999062520-A1 | HIV INTEGRASE INHIBITORS | MERCK & CO., INC. (US) | 1999-12-09 | — | — | WO | claimed |
| EP-1082121-A4 | HIV INTEGRASE INHIBITORS | MERCK & CO INC (US) | 2003-02-05 | — | — | EP | disclosed |
| US-6380249-B1 | HIV integrase inhibitors | MERCK & CO., INC. | 2002-04-30 | — | — | US | disclosed |
| EP-1082121-A1 | HIV INTEGRASE INHIBITORS | Merck & Co., Inc. (US) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999062520-A1 | HIV INTEGRASE INHIBITORS | MERCK & CO., INC. (US) | 1999-12-09 | — | — | WO | disclosed |