Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947316 | 0.86 | STAT3 (0.52) | REN | |
| SCHEMBL6948739 | 0.81 | MTNR1A (0.50) | MTNR1AMTNR1BAPPRENKDM4E | |
| SCHEMBL6948737 | 0.81 | MTNR1A (0.50) | MTNR1AMTNR1BAPPRENKDM4E | |
| SCHEMBL6044557 | 0.80 | MTNR1A (0.47) | MTNR1AMTNR1BAPPKDM4ECYP1A2 | |
| SCHEMBL6045096 | 0.80 | REN (0.48) | RENPTGESALOX5PPARGSLC2A1 | |
| SCHEMBL6044140 | 0.80 | REN (0.48) | RENPTGESALOX5PPARGSLC2A1 | |
| SCHEMBL20577097 | 0.79 | SIGMAR1 (0.47) | REN | |
| SCHEMBL13131318 | 0.79 | APP (0.48) | MTNR1AMTNR1BAPPKDM4ECYP1A2 | |
| SCHEMBL20576388 | 0.78 | MTNR1A (0.47) | MTNR1AMTNR1BAPPRENKDM4E | |
| SCHEMBL20482623 | 0.78 | MEN1 (0.48) | MTNR1AMTNR1BAPPRENKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |