Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 15/20 | 0.60 |
| ▸ | PPARA | Q07869 | 15/20 | 0.60 |
| ▸ | PPARG | P37231 | 10/20 | 0.55 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1459696 | 0.81 | MAPT (0.64) | SMN1; SMN2HTTNPSR1MEN1CYP2C19 | |
| SCHEMBL6944995 | 0.81 | MAPT (0.48) | DGAT1SMN1; SMN2HTTNPSR1MEN1 | |
| SCHEMBL7331958 | 0.78 | MAPT (0.46) | PPARDPPARADGAT1SMN1; SMN2HTT | |
| SCHEMBL24989582 | 0.78 | MAPT (0.60) | SMN1; SMN2HTTNPSR1MEN1CYP2C19 | |
| SCHEMBL5231271 | 0.77 | MAPT (0.67) | SMN1; SMN2HTTNPSR1MEN1CYP2C19 | |
| SCHEMBL12041673 | 0.77 | GPR119 (0.57) | PPARDPPARASMN1; SMN2HTTNPSR1 | |
| SCHEMBL6943134 | 0.76 | DGAT1 (0.58) | DGAT1SMN1; SMN2HTTNPSR1MEN1 | |
| SCHEMBL5546576 | 0.76 | L3MBTL1 (0.62) | PPARDPPARAGPR119MAPT | |
| SCHEMBL27233423 | 0.75 | PPARD (1.00) | PPARDPPARAPPARG | |
| SCHEMBL6936628 | 0.75 | SMN1; SMN2 (0.68) | DGAT1SMN1; SMN2HTTNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889881-B1 | NEW TRIAZOLES AS THERAPEUTIC AGENTS FOR FUNGAL INFECTIONS | NAEJA PHARMACEUTICAL INC (CA) | 2003-04-23 | — | — | EP | disclosed |
| US-6153616-A | Triazoles as therapeutic agents for fungal infections | SYNPHAR LABORATORIES, INC. (CA) | 2000-11-28 | — | — | US | disclosed |