Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946553 | 0.89 | PPARA (0.43) | PPARAPPARDPPARGSLC13A5 | |
| SCHEMBL6948855 | 0.81 | PPARA (0.46) | PPARAPPARDPPARG | |
| SCHEMBL6943259 | 0.81 | REN (0.43) | PPARAPPARDPPARG | |
| SCHEMBL6945792 | 0.77 | REN (0.38) | PPARAPPARGALDH1A1 | |
| SCHEMBL7075858 | 0.77 | REN (0.38) | PPARAPPARGALDH1A1 | |
| SCHEMBL6944108 | 0.75 | BIRC5 (0.39) | PPARAPPARG | |
| SCHEMBL6945137 | 0.75 | BIRC5 (0.42) | PPARAPPARGKDM4E | |
| SCHEMBL6941098 | 0.74 | ALDH1A1 (0.38) | PPARAPPARGKDM4EALDH1A1TDP1 | |
| SCHEMBL6941120 | 0.73 | PPARA (0.39) | PPARAPPARGKDM4EALDH1A1TDP1 | |
| SCHEMBL6947261 | 0.72 | PPARA (0.36) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |