Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 3/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 3/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7075858 | 1.00 | REN (0.38) | RENPPARAPPARGS1PR1MET | |
| SCHEMBL6946553 | 0.83 | PPARA (0.43) | RENPPARAPPARG | |
| SCHEMBL6943259 | 0.81 | REN (0.43) | RENPPARAPPARGPDE4APDE4B | |
| SCHEMBL6943847 | 0.77 | PPARA (0.40) | PPARAPPARGALDH1A1 | |
| SCHEMBL6944108 | 0.75 | BIRC5 (0.39) | RENPPARAPPARGPDE4APDE4B | |
| SCHEMBL6941098 | 0.73 | ALDH1A1 (0.38) | PPARAPPARGPDE4APDE4BPDE4C | |
| SCHEMBL6941120 | 0.73 | PPARA (0.39) | RENPPARAPPARGALDH1A1 | |
| SCHEMBL6945137 | 0.73 | BIRC5 (0.42) | PPARAPPARGS1PR1PDE4APDE4B | |
| SCHEMBL6947261 | 0.72 | PPARA (0.36) | RENPPARAPPARGPDE4APDE4B | |
| SCHEMBL6948686 | 0.69 | CNR2 (0.38) | RENPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | claimed |
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |