SCHEMBL6948855

SCHEMBL6948855

COCOCCc1cc(CCCCCCCC(=O)O)ccc1OC

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 4/20 0.46
PPARG P37231 2/20 0.44
SELP P16109 1/20 0.43
LTB4R Q15722 1/20 0.43
ALOX5 P09917 1/20 0.43
PPARD Q03181 1/20 0.43
MAPT P10636 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10957252 0.83 PPARA (0.52) PPARAPPARGSELPALOX5PPARD
SCHEMBL6943847 0.81 PPARA (0.40) PPARAPPARGPPARD
SCHEMBL7415347 0.80 PPARA (0.58) PPARAPPARGSELPALOX5MAPT
SCHEMBL9175204 0.80 PPARA (0.58) PPARAPPARGSELPALOX5POLB
SCHEMBL7095615 0.79 PPARA (0.59) PPARAPPARGSELPALOX5POLB
SCHEMBL6943609 0.78 PPARA (0.56) PPARAPPARGSELPALOX5POLB
SCHEMBL4454899 0.77 PPARA (0.58) PPARAPPARGPPARD
SCHEMBL9178152 0.77 PPARA (0.51) PPARAPPARGSELPALOX5MAPT
SCHEMBL7410835 0.76 GAA (0.65) SELPALOX5
SCHEMBL12439701 0.76 HPGD (0.61) PPARAPPARGSELPALOX5MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003103653-A1 METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES ELAN PHARMACEUTICALS, INC. (US) 2003-12-18 WO disclosed