Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 6/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940993 | 1.00 | HDAC1 (0.38) | HDAC1HDAC2P2RX7TGM2DPP8 | |
| SCHEMBL6941351 | 0.86 | DPP8 (0.44) | TGM2DPP8DPP9RECQLKMT2A | |
| SCHEMBL6944304 | 0.86 | CACNA1B (0.39) | HDAC1HDAC2P2RX7CTSLPPARG | |
| SCHEMBL6944300 | 0.86 | CACNA1B (0.39) | HDAC1HDAC2P2RX7CTSLPPARG | |
| SCHEMBL8988380 | 0.85 | CTSL (0.39) | HDAC1HDAC2P2RX7TGM2CTSL | |
| SCHEMBL6941021 | 0.82 | DPP8 (0.44) | DPP8DPP9RECQLKMT2A | |
| SCHEMBL6944182 | 0.80 | ALDH1A1 (0.47) | P2RX7CTSLPPARGPPARAKMT2A | |
| SCHEMBL6944179 | 0.80 | ALDH1A1 (0.47) | P2RX7CTSLPPARGPPARAKMT2A | |
| SCHEMBL6946787 | 0.80 | DPP8 (0.42) | DPP8DPP9RECQLKMT2A | |
| SCHEMBL6943983 | 0.80 | DPP8 (0.49) | TGM2DPP8DPP9RECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641795-B9 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2003-01-29 | — | — | EP | disclosed |
| EP-0641795-B1 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5559224-A | Carbepenem derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0641795-A1 | CARBAPENEM DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |