Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944304 | 1.00 | CACNA1B (0.39) | CACNA1BALDH1A1MAPTSMN1; SMN2PPARG | |
| SCHEMBL6940996 | 0.86 | HDAC1 (0.38) | PPARGPPARAP2RX7CTSLHDAC1 | |
| SCHEMBL6940993 | 0.86 | HDAC1 (0.38) | PPARGPPARAP2RX7CTSLHDAC1 | |
| SCHEMBL8988380 | 0.85 | CTSL (0.39) | ALDH1A1PPARGPPARAP2RX7CTSL | |
| SCHEMBL6944179 | 0.85 | ALDH1A1 (0.47) | CACNA1BALDH1A1MAPTSMN1; SMN2PPARG | |
| SCHEMBL6944182 | 0.85 | ALDH1A1 (0.47) | CACNA1BALDH1A1MAPTSMN1; SMN2PPARG | |
| SCHEMBL8436497 | 0.84 | GAA (0.39) | ALDH1A1MAPTSMN1; SMN2GAAMAPK1 | |
| SCHEMBL9127639 | 0.83 | KCNJ1 (0.41) | ALDH1A1MAPTSMN1; SMN2GAAMAPK1 | |
| Hydrochloric Acid SCHEMBL8435888 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPTSMN1; SMN2GAAMAPK1 | |
| SCHEMBL8578872 | 0.81 | SMN1; SMN2 (0.41) | ALDH1A1MAPTSMN1; SMN2HTRA1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641795-B9 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2003-01-29 | — | — | EP | disclosed |
| EP-0641795-B1 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| EP-0641795-A1 | CARBAPENEM DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |