Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | SSTR2 | P30874 | 7/20 | 0.41 |
| ▸ | LTA4H | P09960 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.37 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6765314 | 0.75 | CHEK2 (0.52) | CHEK2MAPTHRH2HRH1 | |
| SCHEMBL8716635 | 0.75 | CHEK2 (0.46) | CHEK2HCRTR1HCRTR2LTA4HKDM4E | |
| SCHEMBL6053346 | 0.75 | CHEK2 (0.58) | CHEK2LTA4HHRH2HRH1 | |
| SCHEMBL7335065 | 0.75 | LTA4H (0.54) | CHEK2LTA4HKDM4EALDH1A1 | |
| SCHEMBL7447377 | 0.74 | LTA4H (0.56) | CHEK2LTA4HAURKBHRH2HRH1 | |
| Hydrochloric Acid SCHEMBL7328923 | 0.74 | LTA4H (0.53) | CHEK2LTA4HKDM4EALDH1A1 | |
| SCHEMBL11713224 | 0.73 | CHEK2 (0.55) | CHEK2SSTR2LTA4HAURKBHRH2 | |
| SCHEMBL3866051 | 0.73 | CHEK2 (0.56) | CHEK2LTA4HHRH2HRH1 | |
| Hydrochloric Acid SCHEMBL7435059 | 0.73 | LTA4H (0.55) | CHEK2LTA4HHRH2HRH1 | |
| SCHEMBL6560708 | 0.72 | MAPT (0.56) | CHEK2LTA4HKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025098-A4 | BENZOTHIOPHENES | LILLY CO ELI (US) | 2003-03-05 | — | — | EP | disclosed |
| EP-1025098-A1 | BENZOTHIOPHENES | ELI LILLY AND COMPANY (US) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999018101-A1 | BENZOTHIOPHENES | ELI LILLY AND COMPANY (US) | 1999-04-15 | — | — | WO | disclosed |