Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7803049 | 0.83 | CES2 (0.41) | CES2CES1ACKR3ALDH1A1KMT2A | |
| SCHEMBL7606342 | 0.83 | CES2 (0.53) | CES2CES1ACKR3L3MBTL1ALDH1A1 | |
| SCHEMBL6945739 | 0.83 | CES2 (0.42) | CES2CES1L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL7804475 | 0.81 | CES2 (0.41) | CES2CES1ACKR3L3MBTL1ALDH1A1 | |
| SCHEMBL6945689 | 0.80 | CES2 (0.53) | CES2CES1ACKR3RIPK1L3MBTL1 | |
| SCHEMBL7804366 | 0.78 | CES2 (0.59) | CES2CES1ACKR3RIPK1L3MBTL1 | |
| SCHEMBL1748151 | 0.77 | CES1 (0.63) | CES2CES1L3MBTL1HTTRAB9A | |
| SCHEMBL6945606 | 0.76 | HTR7 (0.44) | CES2CES1ALDH1A1KMT2ARAB9A | |
| SCHEMBL13151879 | 0.75 | CES2 (0.61) | CES2CES1ACKR3RIPK1L3MBTL1 | |
| SCHEMBL7607142 | 0.75 | CES2 (0.47) | CES2CES1ACKR3L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927719-B1 | Triazole derivative or salt thereof, preparation process thereof as well as pharmaceutical containing said compound | SSP CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| EP-1026154-B1 | Preparation process of difluoroacetophenone derivatives | SSP CO LTD (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6229049-B1 | COUPLING AN ALKYLTHIODIFLUOROACETIC ACID ESTER DERIVATIVE TO A HALOBENZENE DERIVATIVE AS AN INTERMEDIATE FOR 'TRIAZOLES' FUNGICIDES; TREATING MYCOTIC INFECTIOUS DISEASES | SSP CO., LTD. (JP) | 2001-05-08 | — | — | US | disclosed |
| US-6204415-B1 | 2,2-DIFLUORO-2-ETHYLTHIOACETOPHENONE DERIVATIVES OF GIVEN FORMULA WHICH HAVE USE AS INTERMEDIATES TO ANTIMYCOTIC AGENTS | SSP CO., LTD. (JP) | 2001-03-20 | — | — | US | disclosed |
| US-6194592-B1 | AS ANTIMYCOTIC AGENT | SSP CO., LTD. (JP) | 2001-02-27 | — | — | US | disclosed |
| EP-1026154-A2 | Preparation process of difluoroacetophenone derivatives | SSP Co., Ltd. (JP) | 2000-08-09 | — | — | EP | disclosed |
| US-6083968-A | A FUNGICIDE; 1,1-DIFLUORO-1-ETHYL THIENYL OR ETHYL THIENYL OXIDES-2-(2,4-SUBSTITUTED PHENYL)-3-(1H-1,2,4-TRIA ZOL-1-YL)-2-OXY OR HYDROXY COMPOUND | SSP CO., LTD. (JP) | 2000-07-04 | — | — | US | disclosed |
| EP-0927719-A1 | Triazole derivative or salt thereof, preparation process thereof as well as pharmaceutical containing said compound | SSP Co., Ltd. (JP) | 1999-07-07 | — | — | EP | disclosed |