Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.47 |
| ▸ | CES1 | P23141 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7606342 | 0.78 | CES2 (0.53) | CES2CES1L3MBTL1ACKR3KDM4E | |
| SCHEMBL7605938 | 0.78 | CES2 (0.41) | CES2CES1HTR2AHTR2CRAB9A | |
| SCHEMBL7893255 | 0.76 | CES2 (0.52) | CES2CES1L3MBTL1DRD2DRD3 | |
| SCHEMBL6945684 | 0.75 | CES2 (0.50) | CES2CES1L3MBTL1ACKR3RAB9A | |
| SCHEMBL1748151 | 0.75 | CES1 (0.63) | CES2CES1L3MBTL1KDM4ERAB9A | |
| SCHEMBL10832422 | 0.72 | CES2 (0.59) | CES2CES1L3MBTL1HPGDGAA | |
| SCHEMBL7804366 | 0.72 | CES2 (0.59) | CES2CES1L3MBTL1ACKR3GAA | |
| SCHEMBL7886376 | 0.71 | CES2 (0.49) | CES2CES1L3MBTL1DRD2DRD3 | |
| SCHEMBL13151879 | 0.70 | CES2 (0.61) | CES2CES1L3MBTL1ACKR3GAA | |
| SCHEMBL9137806 | 0.69 | CES2 (0.55) | CES2CES1L3MBTL1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1026154-B1 | Preparation process of difluoroacetophenone derivatives | SSP CO LTD (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6229049-B1 | COUPLING AN ALKYLTHIODIFLUOROACETIC ACID ESTER DERIVATIVE TO A HALOBENZENE DERIVATIVE AS AN INTERMEDIATE FOR 'TRIAZOLES' FUNGICIDES; TREATING MYCOTIC INFECTIOUS DISEASES | SSP CO., LTD. (JP) | 2001-05-08 | — | — | US | disclosed |
| US-6184396-B1 | 2-CYCLOPROPYLTHIADIFLUOROMETHYL-2-PHENYLOXIRANE INTERMEDIATES FOR 1-(CYCLOPROPYLTHIA)-2-PHENYL-1,1-(CYCLOPROPYLTHIA)-2-PHENYL-1,1-DIFLUORO-3-(1H-1,2,4-TRIAZOL-1-YL)-2-PROPANOL AND DERIVATIVES; FUNGICIDES; CANDIDA AND ASPERGILLUS | SSP CO., LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| US-6172266-B1 | FUNGICIDES | SSP CO., LTD. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-1026154-A2 | Preparation process of difluoroacetophenone derivatives | SSP Co., Ltd. (JP) | 2000-08-09 | — | — | EP | disclosed |
| US-6040325-A | FUNGICIDES FOR THE PREVENTION AND TREATMENT OF MAMMALIAN MYCOTIC INFECTIONS | SSP CO., LTD. (JP) | 2000-03-21 | — | — | US | disclosed |
| EP-0933368-A1 | Triazole derivative or salt thereof, preparation process thereof and pharmaceutical containing said compound as an effective ingredient (antimycotic) | SSP Co., Ltd. (JP) | 1999-08-04 | — | — | EP | disclosed |