Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15135511 | 0.94 | ALDH1A1 (0.60) | ALDH1A1LMNAPOLBMGLL | |
| SCHEMBL1469483 | 0.86 | LMNA (0.68) | ALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL10290385 | 0.82 | LMNA (0.64) | ALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL4669286 | 0.82 | LMNA (0.64) | ALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL6443856 | 0.82 | LMNA (0.64) | ALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL23049101 | 0.82 | LMNA (0.64) | ALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL118897 | 0.82 | LMNA (0.64) | ALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL8845308 | 0.82 | LMNA (0.64) | ALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL1068467 | 0.82 | ALDH1A1 (0.87) | ALDH1A1LMNAPOLBNPSR1MGLL | |
| SCHEMBL17269992 | 0.82 | LMNA (0.64) | ALDH1A1LMNAPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230058729-A1 | MACROCYCLES AS FACTOR XIA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2023-02-23 | — | — | US | disclosed |
| CN-115003756-A | Resin composition | 松下知识产权经营株式会社 | 2022-09-02 | — | — | CN | disclosed |
| US-11136327-B2 | Macrocycles as factor XIA inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-10-05 | — | — | US | disclosed |
| WO-2021152973-A1 | RESIN COMPOSITION | パナソニックＩＰマネジメント株式会社 | 2021-08-05 | — | — | WO | disclosed |
| EP-3786165-A1 | SYNTHETIC INTERMEDIATES FOR PRODUCING MACROCYCLES AS FACTOR XIA INHIBITORS | Bristol-Myers Squibb Company (US) | 2021-03-03 | — | — | EP | disclosed |
| EP-2534154-B1 | MACROCYCLES AS FACTOR XIA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2020-08-05 | — | — | EP | disclosed |
| US-20200087312-A1 | MACROCYCLES AS FACTOR XIA INHIBITORS | BRISTOL MYERS SQUIBB (US) | 2020-03-19 | — | — | US | disclosed |
| US-20180022753-A1 | MACROCYCLES AS FACTOR XIA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-01-25 | — | — | US | disclosed |
| US-9802939-B2 | Macrocycles as factor XIa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-10-31 | — | — | US | disclosed |
| US-9231274-B2 | Nonaqueous electrolyte solution and lithium secondary battery using same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2016-01-05 | — | — | US | disclosed |
| EP-0973768-A1 | AZOLE COMPOUNDS, THEIR PRODUCTION AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-26 | — | — | EP | disclosed |
| US-5922443-A | Polymeric article, such as a medical catheter, and method for making the same | BOSTON SCIENTIFIC GLENS FALLS CORP. | 1999-07-13 | — | — | US | disclosed |
| WO-1998043970-A1 | AZOLE COMPOUNDS, THEIR PRODUCTION AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |
| EP-0514913-B1 | A polymeric article, such as a medical catheter, and method for making the same | NAMIC CARIBE INC (PR) | 1997-03-12 | — | — | EP | disclosed |
| US-5484565-A | Method for making a medical catheter | NAMIC CARIBE, INC. (PR) | 1996-01-16 | — | — | US | disclosed |
| EP-0514913-A2 | A polymeric article, such as a medical catheter, and method for making the same | NAMIC CARIBE, INC. (PR) | 1992-11-25 | — | — | EP | disclosed |
| EP-0257274-B1 | PROCESS FOR THE ANTISTATIC PRETREATMENT OF POLYAMIDES/POLYIMIDES, THE SO TREATED PRODUCTS AND THEIR USE | BAYER AG (DE) | 1991-08-21 | — | — | EP | disclosed |
| US-4861663-A | Process for antistatic treatment or pretreatment of polyamides, polyimides, antistatically treated or pretreated materials, and the use thereof | BAYER AKTIENGESELLSCHAFT (DE) | 1989-08-29 | — | — | US | disclosed |
| EP-0257274-A2 | Process for the antistatic pretreatment of polyamides/polyimides, the so treated products and their use | BAYER AG (DE) | 1988-03-02 | — | — | EP | disclosed |
| EP-0058331-B1 | POLYAMIDE MOULDING COMPOUNDS | BAYER AG (DE) | 1985-06-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200087312-A1 | MACROCYCLES AS FACTOR XIA INHIBITORS | TFPI, TFPI2, F11 | ALDH1A1 4598/4885LMNA 1757/4885POLB 4561/4885 |
| US-11136327-B2 | Macrocycles as factor XIA inhibitors | TFPI, TFPI2, F11 | ALDH1A1 4598/4885LMNA 1757/4885POLB 4561/4885 |
| US-20180022753-A1 | MACROCYCLES AS FACTOR XIA INHIBITORS | TFPI, TFPI2, F11 | ALDH1A1 4598/4885LMNA 1757/4885POLB 4561/4885 |
| US-20230058729-A1 | MACROCYCLES AS FACTOR XIA INHIBITORS | TFPI, TFPI2, F11 | ALDH1A1 4598/4885LMNA 1757/4885POLB 4561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.