Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6443856 | 1.00 | LMNA (0.64) | LMNAPOLBALDH1A1NPSR1MEN1 | |
| SCHEMBL6443863 | 1.00 | LMNA (0.64) | LMNAPOLBALDH1A1NPSR1MEN1 | |
| SCHEMBL8460521 | 0.94 | LMNA (0.57) | LMNAPOLBALDH1A1 | |
| SCHEMBL1469483 | 0.84 | LMNA (0.68) | LMNAPOLBALDH1A1NPSR1MEN1 | |
| SCHEMBL6945700 | 0.82 | ALDH1A1 (0.67) | LMNAPOLBALDH1A1NPSR1 | |
| SCHEMBL5078328 | 0.82 | LMNA (0.57) | LMNAPOLBALDH1A1NPSR1 | |
| SCHEMBL25323826 | 0.81 | LMNA (0.70) | LMNAPOLBALDH1A1NPSR1 | |
| SCHEMBL8845308 | 0.81 | LMNA (0.64) | LMNAPOLBALDH1A1NPSR1MEN1 | |
| SCHEMBL10290385 | 0.81 | LMNA (0.64) | LMNAPOLBALDH1A1NPSR1MEN1 | |
| SCHEMBL23049101 | 0.81 | LMNA (0.64) | LMNAPOLBALDH1A1NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5187306-A | Reacting unsaturated amides with metallic bases to form metal salts, which are reacted with halogenated formic acid esters | NIPPON PAINT CO., LTD. (JP) | 1993-02-16 | — | — | US | claimed |
| US-20210040041-A1 | QUINOLINE DERIVATIVES AND PREPARATION METHODS AND USES THEREOF | Dongguan HEC Pesticides R&D Co., Ltd. (CN) | 2021-02-11 | — | — | US | disclosed |
| US-20080194629-A1 | 3-Mono-and 3,5-Disubstituted Piperidine Derivatives as Renin Inhibitors | BAESCHLIN DANIEL KASPAR | 2008-08-14 | — | — | US | disclosed |
| CN-101171248-A | 3-mono- and 3,5-disubstituted piperidine derivatives as renin inhibitors | NOVARTIS AG (CH) | 2008-04-30 | — | — | CN | disclosed |
| EP-1879882-A1 | 3 -M0N0- AND 3 , 5-DISUBSTITUTED PIPERIDINE DERIVATIVES AS RENIN INHIBITORS | Novartis AG (CH) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117183-A1 | 3 -M0N0- AND 3 , 5-DISUBSTITUTED PIPERIDINE DERIVATIVES AS RENIN INHIBITORS | NOVARTIS AG (CH) | 2006-11-09 | — | — | WO | disclosed |
| US-20050014787-A1 | 5-amidino-2-hydroxybenzenesulfonamide derivatives medicinal compoistions containing the same medicinal use thereof and intermediates in the production thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
| EP-1443041-A1 | 5-AMIDINO-2-HYDROXYBENZENESULFONAMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME, MEDICINAL USE THEREOF AND INTERMEDIATES IN THE PRODUCTION THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2004-08-04 | — | — | EP | disclosed |
| EP-1392315-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100410-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | disclosed |
| US-5434296-A | Reacting carbamate with metallic base to form salt; reacting with unsaturated acid halide to acylate | NIPPON PAINT CO., LTD. (JP) | 1995-07-18 | — | — | US | disclosed |
| EP-0465162-B1 | Process for producing unsaturated carbamic acid esters | NIPPON PAINT CO LTD (JP) | 1994-12-07 | — | — | EP | disclosed |
| US-5187306-A | Reacting unsaturated amides with metallic bases to form metal salts, which are reacted with halogenated formic acid esters | NIPPON PAINT CO., LTD. (JP) | 1993-02-16 | — | — | US | disclosed |
| EP-0465162-A1 | Process for producing unsaturated carbamic acid esters | NIPPON PAINT CO., LTD. (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-4376731-A | 2-NITRILES THEREOF | BOEHRINGER MANNHEIM GMBH (DE) | 1983-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040041-A1 | QUINOLINE DERIVATIVES AND PREPARATION METHODS AND USES THEREOF | NQO2, RDX, RIN1 | LMNA 3149/4885POLB 3689/4885ALDH1A1 1655/4885 |
| US-20050014787-A1 | 5-amidino-2-hydroxybenzenesulfonamide derivatives medicinal compoistions containing the same medicinal use thereof and intermediates in the production thereof | F2, HYPK, F10 | LMNA 1435/4885POLB 3016/4885ALDH1A1 3117/4885 |
| US-20080194629-A1 | 3-Mono-and 3,5-Disubstituted Piperidine Derivatives as Renin Inhibitors | REN, ACE, AGTR1 | LMNA 1399/4885POLB 1855/4885ALDH1A1 231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.