Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.38 |
| ▸ | REN | P00797 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 7/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6943259 | 0.82 | REN (0.43) | RENPPARGPPARA | |
| SCHEMBL6941098 | 0.81 | ALDH1A1 (0.38) | PPARGPPARA | |
| SCHEMBL6944108 | 0.81 | BIRC5 (0.39) | RENPPARGPPARA | |
| SCHEMBL6941120 | 0.81 | PPARA (0.39) | RENPPARGPPARA | |
| SCHEMBL6946620 | 0.79 | REN (0.51) | REN | |
| SCHEMBL6946553 | 0.78 | PPARA (0.43) | RENPPARGPPARA | |
| SCHEMBL6947261 | 0.77 | PPARA (0.36) | RENPPARGPPARA | |
| SCHEMBL6945137 | 0.75 | BIRC5 (0.42) | PPARGPPARA | |
| SCHEMBL6946075 | 0.74 | CYP3A4 (0.41) | RENHPGD | |
| SCHEMBL6943661 | 0.73 | LMNA (0.47) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |