Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL6941246 | 0.98 | THRB (0.34) | THRBRECQLMEN1MAPTKMT2A | |
| SCHEMBL3480852 | 0.88 | CASP1 (0.37) | THRBRECQLMEN1MAPTKMT2A | |
| SCHEMBL5253253 | 0.74 | CASP1 (0.40) | THRBRECQLMEN1MAPTKMT2A | |
| Ethylene Glycol SCHEMBL10714154 | 0.73 | ALDH1A1 (0.52) | THRBMEN1MAPTKMT2ATDP1 | |
| SCHEMBL23878080 | 0.72 | ALDH1A1 (0.40) | THRBRECQLMEN1MAPTKMT2A | |
| SCHEMBL25941241 | 0.72 | PTPN11 (0.39) | RECQLMEN1MAPTKMT2APOLB | |
| SCHEMBL7691805 | 0.72 | NQO2 (0.33) | RECQLKMT2ATDP1ALDH1A1HPGD | |
| SCHEMBL3679569 | 0.71 | CA1 (0.46) | THRBRECQLMEN1MAPTKMT2A | |
| SCHEMBL3677559 | 0.71 | CA14 (0.41) | THRBRECQLTDP1CASP1ALDH1A1 | |
| Ethylene Glycol SCHEMBL28777410 | 0.71 | MAPT (0.61) | THRBMEN1MAPTKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999203-B1 | Novel developer in oxidative hair dyeing | CLAIROL INC (US) | 2003-02-26 | — | — | EP | disclosed |
| EP-0999203-A1 | Novel developer in oxidative hair dyeing | Bristol-Myers Squibb Company (US) | 2000-05-10 | — | — | EP | disclosed |