Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | CASP1 | P29466 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29358097 | 0.98 | THRB (0.36) | THRBTDP1RECQLMEN1MAPT | |
| SCHEMBL111094 | 0.98 | THRB (0.36) | THRBTDP1RECQLMEN1MAPT | |
| Hydrochloric Acid SCHEMBL19549198 | 0.96 | MAPT (0.39) | THRBTDP1RECQLMEN1MAPT | |
| Sulfuric Acid SCHEMBL6947452 | 0.89 | ALDH1A1 (0.50) | THRBTDP1RECQLMEN1MAPT | |
| SCHEMBL5181377 | 0.83 | PYGL (0.39) | THRBTDP1RECQLMEN1MAPT | |
| SCHEMBL30120579 | 0.82 | PDE2A (0.39) | THRBTDP1RECQLMEN1MAPT | |
| SCHEMBL19972208 | 0.82 | THRB (0.34) | THRBTDP1RECQLMEN1MAPT | |
| SCHEMBL109440 | 0.82 | CYP3A4 (0.43) | THRBTDP1RECQLMEN1MAPT | |
| Hydrochloric Acid SCHEMBL27813642 | 0.82 | PYGL (0.38) | THRBTDP1RECQLMEN1MAPT | |
| Hydrochloric Acid SCHEMBL27940325 | 0.82 | PYGL (0.38) | THRBTDP1RECQLMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999203-B1 | Novel developer in oxidative hair dyeing | CLAIROL INC (US) | 2003-02-26 | — | — | EP | disclosed |
| EP-0999203-A1 | Novel developer in oxidative hair dyeing | Bristol-Myers Squibb Company (US) | 2000-05-10 | — | — | EP | disclosed |