Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6943380 | 0.84 | TSHR (0.42) | CYP3A4TSHRCA1CA2PDE10A | |
| SCHEMBL29358097 | 0.83 | THRB (0.36) | CYP3A4TSHRCA1CA2PDE10A | |
| SCHEMBL111094 | 0.83 | THRB (0.36) | CYP3A4TSHRCA1CA2PDE10A | |
| Hydrochloric Acid SCHEMBL19549198 | 0.82 | MAPT (0.39) | CYP3A4TSHRCA1CA2PDE10A | |
| SCHEMBL6946033 | 0.82 | THRB (0.35) | CYP3A4TSHRHPGDRECQLTDP1 | |
| SCHEMBL17774758 | 0.80 | CA1 (0.42) | CYP3A4TSHRCA1CA2PDE10A | |
| SCHEMBL9150253 | 0.79 | CYP3A4 (0.42) | CYP3A4TSHRHPGDRECQLTDP1 | |
| SCHEMBL18826532 | 0.79 | CA1 (0.48) | CYP3A4TSHRCA1CA2PDE10A | |
| SCHEMBL8016400 | 0.78 | ADRB2 (0.42) | CA1CA2PDE10AADRB2ADRB1 | |
| SCHEMBL5181377 | 0.78 | PYGL (0.39) | CYP3A4TSHRCA1CA2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1609 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11918671-B2 | Multi-tone hair dyeing method in three steps | HENKEL AG & CO. KGAA (DE) | 2024-03-05 | — | — | US | claimed |
| US-20230031764-A1 | MULTI-TONE HAIR DYEING METHOD IN THREE STEPS | HENKEL AG & CO. KGAA (DE) | 2023-02-02 | — | — | US | claimed |
| EP-3082751-B1 | TETRASUBSTITUTED PYRIMIDINE DERIVATIVES IN OXIDATIVE DYEING PREPARATIONS | HENKEL AG & CO KGAA (DE) | 2018-09-19 | — | — | EP | claimed |
| US-9636288-B2 | Means for oxidative dyeing of keratin fibers containing novel tetra-substituted derivatives of pyrimidine | HENKEL AG & CO. KGAA (DE) | 2017-05-02 | — | — | US | claimed |
| EP-3082751-A1 | MEANS FOR OXIDATIVE DYEING OF KERATIN FIBERS CONTAINING NOVEL TETRA-SUBSTITUTED DERIVATIVES OF PYRIMIDINE | Henkel AG & Co. KGaA (DE) | 2016-10-26 | — | — | EP | claimed |
| US-20160296447-A1 | MEANS FOR OXIDATIVE DYEING OF KERATIN FIBERS CONTAINING NOVEL TETRA-SUBSTITUTED DERIVATIVES OF PYRIMIDINE | HENKEL AG & CO. KGAA (DE) | 2016-10-13 | — | — | US | claimed |
| WO-2015090292-A1 | MEANS FOR OXIDATIVE DYEING OF KERATIN FIBERS CONTAINING NOVEL TETRA-SUBSTITUTED DERIVATIVES OF PYRIMIDINE | HENKEL AG & CO. KGAA (DE) | 2015-06-25 | — | — | WO | claimed |
| EP-1359890-A4 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G CLAIROL INC (US) | 2009-08-12 | — | — | EP | claimed |
| US-7413579-B2 | Method for dyeing fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-08-19 | — | — | US | claimed |
| EP-1759735-B1 | Method of selectively dyeing portions of hair | HENKEL KGAA (DE) | 2007-12-05 | — | — | EP | claimed |
| WO-2002003938-A1 | IODO-CONTAINING ORGANIC COUPLERS FOR USE IN OXIDATIVE HAIR DYEING | CLAIROL INCORPORATED (US) | 2002-01-17 | — | — | WO | claimed |
| EP-1129688-A1 | Hair coloring composition using an inorganic peroxymonosulfate salt as an oxidation agent. | Bristol-Myers Squibb Company (US) | 2001-09-05 | — | — | EP | claimed |
| WO-2001056538-A1 | NOVEL COUPLER FOR USE IN OXIDATIVE HAIR DYEING | P&G-CLAIROL, INC. (US) | 2001-08-09 | — | — | WO | claimed |
| WO-2001054656-A1 | NOVEL PRIMARY INTERMEDIATE FOR USE IN OXIDATIVE HAIR DYEING | P&G-CLAIROL, INC. (US) | 2001-08-02 | — | — | WO | claimed |
| EP-1120105-A2 | 1-(2,5-diaminophenyl)ethanol and its use in oxidative hair dyeing | Bristol-Myers Squibb Company (US) | 2001-08-01 | — | — | EP | claimed |
| US-6264703-B1 | FOR DYEING HAIR | CLAIROL INCORPORATED | 2001-07-24 | — | — | US | claimed |
| US-6200353-B1 | Coupler for use in oxidative hair dyeing | BRISTOL MYERS SQUIBB COMPANY | 2001-03-13 | — | — | US | claimed |
| EP-1048290-A2 | Oxidative hair dye compositions with conditioning and enhanced color deposition | Bristol-Myers Squibb Company (US) | 2000-11-02 | — | — | EP | claimed |
| EP-1006104-A1 | P-aminophenol substitute and its use in oxidation dye formulations | Bristol-Myers Squibb Company (US) | 2000-06-07 | — | — | EP | claimed |
| US-5980584-A | NONTOXIC; REPLACEMENT FOR P-AMINOPHENOL IN OXIDATIVE HAIR DYE SYSTEMS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-11-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160296447-A1 | MEANS FOR OXIDATIVE DYEING OF KERATIN FIBERS CONTAINING NOVEL TETRA-SUBSTITUTED DERIVATIVES OF PYRIMIDINE | KRT18, TK1, DPYD | CYP3A4 1401/4885TSHR 2998/4885CA1 1854/4885 |
| US-11918671-B2 | Multi-tone hair dyeing method in three steps | TYR, HAO2, HAAO | CYP3A4 2007/4885TSHR 3526/4885CA1 525/4885 |
| US-20230031764-A1 | MULTI-TONE HAIR DYEING METHOD IN THREE STEPS | TYR, HAO2, HAAO | CYP3A4 2007/4885TSHR 3526/4885CA1 525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.