Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944825 | 0.92 | ALDH1A1 (0.35) | CYP3A4ALDH1A1REN | |
| SCHEMBL6943259 | 0.78 | REN (0.43) | REN | |
| SCHEMBL6941098 | 0.77 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6944108 | 0.76 | BIRC5 (0.39) | REN | |
| SCHEMBL6941120 | 0.76 | PPARA (0.39) | ALDH1A1SMN1; SMN2RENMEN1KMT2A | |
| SCHEMBL6948686 | 0.74 | CNR2 (0.38) | RENHPGD | |
| SCHEMBL6947261 | 0.73 | PPARA (0.36) | REN | |
| SCHEMBL6943661 | 0.73 | LMNA (0.47) | ALDH1A1REN | |
| SCHEMBL6946553 | 0.72 | PPARA (0.43) | REN | |
| SCHEMBL6945137 | 0.70 | BIRC5 (0.42) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |