Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.38 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.37 |
| ▸ | GRM6 | O15303 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 2/20 | 0.35 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3278753 | 0.84 | SLC7A5 (0.41) | GRIA1GRIA2GRIA3ALOX15KMT2A | |
| SCHEMBL10280445 | 0.75 | KEAP1 (0.35) | CYP1A2CYP2C9 | |
| SCHEMBL1983029 | 0.65 | SLC7A5 (0.38) | GRIA1GRIA2GRIA3GRIA4CYP1A2 | |
| SCHEMBL6009735 | 0.62 | USP2 (0.42) | GRIA1GRIA2GRIA3GRIA4ALOX15 | |
| SCHEMBL602426 | 0.61 | GSR (0.68) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8068164 | 0.61 | GSR (0.68) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| Homophenylalanine SCHEMBL44312 | 0.61 | ALPI (0.64) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| Homophenylalanine SCHEMBL130567 | 0.61 | ALPI (0.64) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| Homophenylalanine SCHEMBL1078733 | 0.61 | ALPI (0.64) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| Homophenylalanine SCHEMBL44311 | 0.61 | ALPI (0.64) | GRIK1GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902011-B1 | GAMMA-OXO-HOMOPHENYLALANINE DERIVATIVES AND PROCESS FOR PRODUCING HOMOPHENYLALANINE DERIVATIVES BY REDUCING THE SAME | KANEKA CORP (JP) | 2003-05-21 | — | — | EP | claimed |
| US-5981794-A | REACTING A BETA-BENZOYLACRYLIC ACID DERIVATIVE WITH A 1-ARYLETHYLAMINE DERIVATIVE | KANEKA CORPORATION (JP) | 1999-11-09 | — | — | US | claimed |
| EP-0902011-A1 | $g(g)-OXO-HOMOPHENYLALANINE DERIVATIVES AND PROCESS FOR PRODUCING HOMOPHENYLALANINE DERIVATIVES BY REDUCING THE SAME | Kaneka Corporation (JP) | 1999-03-17 | — | — | EP | claimed |
| EP-0902011-B1 | GAMMA-OXO-HOMOPHENYLALANINE DERIVATIVES AND PROCESS FOR PRODUCING HOMOPHENYLALANINE DERIVATIVES BY REDUCING THE SAME | KANEKA CORP (JP) | 2003-05-21 | — | — | EP | disclosed |
| US-5981794-A | REACTING A BETA-BENZOYLACRYLIC ACID DERIVATIVE WITH A 1-ARYLETHYLAMINE DERIVATIVE | KANEKA CORPORATION (JP) | 1999-11-09 | — | — | US | disclosed |
| US-5981794-A | REACTING A BETA-BENZOYLACRYLIC ACID DERIVATIVE WITH A 1-ARYLETHYLAMINE DERIVATIVE | KANEKA CORPORATION (JP) | 1999-11-09 | — | — | US | disclosed |
| US-5981794-A | REACTING A BETA-BENZOYLACRYLIC ACID DERIVATIVE WITH A 1-ARYLETHYLAMINE DERIVATIVE | KANEKA CORPORATION (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0902011-A1 | $g(g)-OXO-HOMOPHENYLALANINE DERIVATIVES AND PROCESS FOR PRODUCING HOMOPHENYLALANINE DERIVATIVES BY REDUCING THE SAME | Kaneka Corporation (JP) | 1999-03-17 | — | — | EP | disclosed |
| EP-0902011-A1 | $g(g)-OXO-HOMOPHENYLALANINE DERIVATIVES AND PROCESS FOR PRODUCING HOMOPHENYLALANINE DERIVATIVES BY REDUCING THE SAME | Kaneka Corporation (JP) | 1999-03-17 | — | — | EP | disclosed |