Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.41 |
| ▸ | EBP | Q15125 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2408362 | 0.85 | ATM (0.56) | KDM4EATMSTAT3 | |
| SCHEMBL16381568 | 0.80 | SIGMAR1 (0.52) | KDM4EATMSIGMAR1EBPTMEM97 | |
| SCHEMBL16973663 | 0.80 | SIGMAR1 (0.50) | RENKDM4EATMSIGMAR1STAT3 | |
| SCHEMBL16381566 | 0.79 | ATM (0.47) | RENKDM4EATMSIGMAR1EBP | |
| SCHEMBL15173349 | 0.78 | CA2 (0.47) | RENKDM4EATMSIGMAR1EBP | |
| SCHEMBL3757267 | 0.77 | STAT3 (0.52) | RENSIGMAR1STAT3 | |
| SCHEMBL6947316 | 0.77 | STAT3 (0.52) | RENSTAT3 | |
| SCHEMBL5076405 | 0.76 | STAT3 (0.48) | RENSIGMAR1TMEM97STAT3 | |
| SCHEMBL88960 | 0.76 | CA2 (0.48) | RENKDM4ESIGMAR1EBPTMEM97 | |
| SCHEMBL14114916 | 0.76 | ALOX15 (0.55) | RENSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |