Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.44 |
| ▸ | REN | P00797 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2426917 | 0.88 | REN (0.52) | SIGMAR1REN | |
| SCHEMBL16973663 | 0.85 | SIGMAR1 (0.50) | STAT3SIGMAR1REN | |
| SCHEMBL27930278 | 0.84 | STAT3 (0.45) | STAT3SIGMAR1REN | |
| SCHEMBL6947316 | 0.83 | STAT3 (0.52) | STAT3REN | |
| SCHEMBL3757267 | 0.83 | STAT3 (0.52) | STAT3SIGMAR1REN | |
| SCHEMBL29521379 | 0.79 | REN (0.48) | REN | |
| SCHEMBL2810242 | 0.79 | REN (0.48) | REN | |
| SCHEMBL16381568 | 0.78 | SIGMAR1 (0.52) | SIGMAR1TMEM97 | |
| SCHEMBL17732239 | 0.77 | SIGMAR1 (0.52) | SIGMAR1REN | |
| SCHEMBL16381566 | 0.76 | ATM (0.47) | SIGMAR1TMEM97REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200390-B1 | PRODUCTION OF N-SUBSTITUTED 2,7-DIALKYL-4-HYDROXY-5-AMINO-8-ARYL-OCTANOYLAMIDES | SPEEDEL PHARMA AG (CH) | 2008-08-27 | — | — | EP | disclosed |
| US-7132569-B2 | Preparation of N-substituted 2,7-dialkyl-4-hydroxy-5-amino-8-aryl-octanoyl amides | SPEEDEL PHARMA AG (CH) | 2006-11-07 | — | — | US | disclosed |
| US-7009078-B1 | Production of N-substituted 2,7-dialkyl-4-hydroxy-5-amino-8-arly-octanoylamides | SPEEDEL PHARMA AG (CH) | 2006-03-07 | — | — | US | disclosed |
| US-20060041169-A1 | PREPARATION OF N-SUBSTITUTED 2,7-DIALKYL-4-HYDROXY-5-AMINO-8-ARYL-OCTANOYL AMIDES | NODEN PHARMA DAC (IE) | 2006-02-23 | — | — | US | disclosed |
| US-6800769-B2 | CHEMICAL INTERMEDIATES | SPEEDEL PHARMA AG (CH) | 2004-10-05 | — | — | US | disclosed |
| EP-1303478-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED OCTANOYL AMIDES | SPEEDEL PHARMA AG (CH) | 2004-05-26 | — | — | EP | disclosed |
| US-20030181765-A1 | Process for the preparation of substituted octanoyl amides | NODEN PHARMA DAC (IE) | 2003-09-25 | — | — | US | disclosed |
| EP-1303478-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED OCTANOYL AMIDES | Speedel Pharma AG (CH) | 2003-04-23 | — | — | EP | disclosed |
| EP-1200390-A1 | PRODUCTION OF N-SUBSTITUTED 2,7-DIALKYL-4-HYDROXY-5-AMINO-8-ARYL-OCTANOYLAMIDES | Speedel Pharma AG (CH) | 2002-05-02 | — | — | EP | disclosed |
| WO-2002008172-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED OCTANOYL AMIDES | SPEEDEL PHARMA AG (CH) | 2002-01-31 | — | — | WO | disclosed |
| WO-2001009083-A1 | PRODUCTION OF N-SUBSTITUTED 2,7-DIALKYL-4-HYDROXY-5-AMINO-8-ARYL-OCTANOYLAMIDES | SPEEDEL PHARMA AG (CH) | 2001-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060041169-A1 | PREPARATION OF N-SUBSTITUTED 2,7-DIALKYL-4-HYDROXY-5-AMINO-8-ARYL-OCTANOYL AMIDES | AOC3, AOC2, AOC1 | STAT3 4865/4885SIGMAR1 93/4885KCNH2 41/4885 |
| US-20030181765-A1 | Process for the preparation of substituted octanoyl amides | CEL, HDHD5, LPO | STAT3 1853/4885SIGMAR1 1195/4885KCNH2 475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.