Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 3/20 | 0.44 |
| ▸ | FLT4 | P35916 | 3/20 | 0.44 |
| ▸ | KDR | P35968 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559853 | 0.81 | CES2 (0.39) | SMN1; SMN2MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL14432141 | 0.79 | GPR27 (0.36) | GPR27TSHRMEN1MAPTKMT2A | |
| SCHEMBL4678894 | 0.78 | BCHE (0.33) | SMN1; SMN2MAPTKMT2AALDH1A1HPGD | |
| SCHEMBL5745612 | 0.78 | HPGD (0.43) | SMN1; SMN2MYCKMT2APOLBHPGD | |
| SCHEMBL107882 | 0.77 | FLT1 (0.51) | FLT1FLT4KDRCYP11B2RAB9A | |
| SCHEMBL250256 | 0.75 | FLT1 (0.53) | FLT1FLT4KDRCYP11B2RAB9A | |
| SCHEMBL30628195 | 0.74 | FLT1 (0.51) | FLT1FLT4KDRCYP11B2RAB9A | |
| SCHEMBL4574528 | 0.74 | FLT1 (0.51) | FLT1FLT4KDRCYP11B2RAB9A | |
| SCHEMBL109654 | 0.74 | SMN1; SMN2 (0.63) | FLT1FLT4KDRRAB9ASMN1; SMN2 | |
| SCHEMBL11535595 | 0.74 | CES2 (0.50) | TSHRMAPTALOX15ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1119559-B1 | 3-PHENYL-PYRONES | BAYER CROPSCIENCE AG (DE) | 2003-11-26 | — | — | EP | disclosed |
| US-6441030-B1 | PESTICIDES, FUNGICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-27 | — | — | US | disclosed |
| EP-1119559-A1 | 3-PHENYL-PYRONES | Bayer Aktiengesellschaft (DE) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000021946-A1 | 3-PHENYL-PYRONES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-04-20 | — | — | WO | disclosed |