Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | FDPS | P14324 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946483 | 0.85 | MEN1 (0.46) | CYP1A2CYP3A4CYP2C19BLMPMP22 | |
| SCHEMBL6946985 | 0.83 | PPARA (0.38) | CYP1A2CYP3A4CYP2C19BLMPMP22 | |
| SCHEMBL6947449 | 0.83 | HRH3 (0.46) | CYP1A2CYP3A4CYP2C19BLMPMP22 | |
| SCHEMBL6948494 | 0.80 | MEN1 (0.43) | CYP1A2CYP3A4CYP2C19BLMPMP22 | |
| SCHEMBL6948498 | 0.76 | MEN1 (0.43) | CYP1A2CYP3A4CYP2C19BLMPMP22 | |
| SCHEMBL7134517 | 0.73 | PPARA (0.40) | CYP1A2CYP3A4CYP2C19BLMPMP22 | |
| SCHEMBL21601216 | 0.71 | PDK2 (0.53) | CYP1A2CYP3A4CYP2C19BLMPMP22 | |
| SCHEMBL6943326 | 0.70 | PPARA (0.41) | CYP1A2CYP3A4CYP2C19BLMPMP22 | |
| SCHEMBL6950101 | 0.68 | MMP2 (0.41) | CYP1A2CYP3A4CYP2C19BLMPMP22 | |
| SCHEMBL7497814 | 0.68 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2C19BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030836-B1 | HYDROXAMIC AND CARBOXYLIC ACID DERIVATIVES HAVING MMP AND TNF INHIBITORY ACTIVITY | DARWIN DISCOVERY LTD (GB) | 2003-01-29 | — | — | EP | claimed |