Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 18/20 | 0.41 |
| ▸ | SUZ12 | Q15022 | 13/20 | 0.40 |
| ▸ | EZH2 | Q15910 | 13/20 | 0.40 |
| ▸ | RBBP4 | Q09028 | 6/20 | 0.40 |
| ▸ | AEBP2 | Q6ZN18 | 6/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944965 | 0.88 | MTNR1A (0.52) | MTNR1AMTNR1B | |
| Cyclopropane SCHEMBL6948950 | 0.85 | MTNR1A (0.39) | MTNR1AMTNR1B | |
| SCHEMBL30289543 | 0.83 | EED (0.46) | EEDSUZ12EZH2RBBP4AEBP2 | |
| SCHEMBL17841424 | 0.83 | EED (0.46) | EEDSUZ12EZH2RBBP4AEBP2 | |
| Cyclopropane SCHEMBL6950925 | 0.79 | MTNR1A (0.52) | EEDMTNR1AMTNR1B | |
| SCHEMBL6955732 | 0.77 | EED (0.41) | EEDSUZ12EZH2 | |
| SCHEMBL6955724 | 0.76 | EED (0.42) | EEDSUZ12EZH2RBBP4AEBP2 | |
| Hydrochloric Acid SCHEMBL6956077 | 0.76 | EED (0.40) | EEDSUZ12EZH2 | |
| Cyclopropane SCHEMBL6952259 | 0.75 | HTR3E (0.34) | EEDMTNR1A | |
| SCHEMBL6953856 | 0.72 | MTNR1A (0.52) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901483-B1 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LTD (GB) | 2003-07-09 | — | — | EP | claimed |