Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 18/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 17/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6953856 | 0.88 | MTNR1A (0.52) | MTNR1AMTNR1B | |
| Cyclopropane SCHEMBL6947276 | 0.85 | EED (0.41) | MTNR1AMTNR1B | |
| SCHEMBL6948988 | 0.84 | MTNR1A (0.50) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| Cyclopropane SCHEMBL6950925 | 0.79 | MTNR1A (0.52) | MTNR1AMTNR1B | |
| Cyclopropane SCHEMBL6952259 | 0.77 | HTR3E (0.34) | MTNR1A | |
| SCHEMBL6956175 | 0.76 | MTNR1B (0.37) | MTNR1AMTNR1B | |
| SCHEMBL6956181 | 0.76 | HTR2C (0.35) | — | |
| SCHEMBL18301929 | 0.76 | AKR1B1 (0.47) | MTNR1AMTNR1BABCB11SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6955982 | 0.74 | HTR2C (0.35) | — | |
| SCHEMBL6950270 | 0.72 | MTNR1B (0.56) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901483-B1 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LTD (GB) | 2003-07-09 | — | — | EP | claimed |