SCHEMBL14713399

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12640739	1.00	THRB (0.35)	THRBALDH1A1TP53TSHRHIF1A
	SCHEMBL14713388	0.99	ALDH1A1 (0.35)	THRBALDH1A1TP53TSHRHIF1A
	SCHEMBL14713292	0.96	POLB (0.34)	THRBALDH1A1TP53TSHRHIF1A
	SCHEMBL14713286	0.95	POLB (0.33)	THRBALDH1A1TP53TSHRHIF1A
	SCHEMBL29781936	0.93	THRB (0.33)	THRBALDH1A1TP53TSHRHIF1A
	SCHEMBL18095075	0.91	ALDH1A1 (0.38)	THRBALDH1A1TP53TSHRHIF1A
	SCHEMBL6947345	0.89	ALDH1A1 (0.41)	THRBALDH1A1TP53TSHRHIF1A
	SCHEMBL16664312	0.89	ALDH1A1 (0.41)	THRBALDH1A1TP53TSHRHIF1A
	SCHEMBL29781934	0.89	ALDH1A1 (0.33)	THRBALDH1A1TP53TSHRHIF1A
	SCHEMBL21732988	0.89	—	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.