SCHEMBL515466

SCHEMBL515466

O=[N+]([O-])c1ccc(CO)cc1[N+](=O)[O-]

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.54
ALDH1A1 P00352 2/20 0.54
TSHR P16473 3/20 0.50
CYP3A4 P08684 1/20 0.50
CASP6 P55212 1/20 0.50
TTR P02766 1/20 0.47
POLB P06746 1/20 0.45
HTR1A P08908 1/20 0.43
DRD2 P14416 1/20 0.43
HTR2A P28223 1/20 0.43
GPR35 Q9HC97 1/20 0.42
SNCA P37840 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
MAPK1 P28482 2/20 0.40
ATM Q13315 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12633802 0.89 MAPT (0.46) MAPTALDH1A1TSHRCYP3A4CASP6
SCHEMBL31612277 0.84 ALDH1A1 (0.51) MAPTALDH1A1TSHRTTRPOLB
SCHEMBL1736272 0.84 POLB (0.62) MAPTALDH1A1TSHRPOLBGPR35
SCHEMBL2345266 0.84 GPR35 (0.58) MAPTALDH1A1TSHRCYP3A4TTR
SCHEMBL10608137 0.84 TSHR (0.58) MAPTALDH1A1TSHRCYP3A4CASP6
SCHEMBL1589851 0.84 ALDH1A1 (0.51) MAPTALDH1A1TSHRTTRPOLB
SCHEMBL10270605 0.82 TSHR (0.58) MAPTALDH1A1TSHRCYP3A4TTR
SCHEMBL279049 0.82 ALDH1A1 (0.50) MAPTALDH1A1TSHRCYP3A4TTR
SCHEMBL715634 0.82 ALDH1A1 (0.57) MAPTALDH1A1TSHRCYP3A4TTR
SCHEMBL713941 0.82 TSHR (0.54) MAPTALDH1A1TSHRCYP3A4TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4758312-A Adding colorless electrochemically active compound having positive reduction potential NALCO CHEMICAL COMPANY (US) 1988-07-19 US claimed
US-20250074944-A1 ACYLATED tRNA, INTRODUCTION OF PHARMACOLOGICALLY ACTIVE MOTIF IN PEPTIDE USING RIBOSOME CATALYSIS AND METHOD OF PREPARING SAME POSTECH Research and Business Development Foundation (KR) 2025-03-06 US disclosed
CN-105008348-B Pyrazolylbenzo [ D ] imidazole derivatives 赛隆制药股份公司 2018-07-10 CN disclosed
US-9849196-B2 Methods and compositions for altering photophysical properties of fluorophores via proximal quenching CORNELL UNIVERSITY (US) 2017-12-26 US disclosed
US-9776988-B2 Pyrazolylbenzo[d]imidazole derivatives CELON PHARMA S.A. (PL) 2017-10-03 US disclosed
US-9776988-B2 Pyrazolylbenzo[d]imidazole derivatives CELON PHARMA S.A. (PL) 2017-10-03 US disclosed
US-9776988-B2 Pyrazolylbenzo[d]imidazole derivatives CELON PHARMA S.A. (PL) 2017-10-03 US disclosed
US-9631096-B2 Dye compositions, methods of preparation, conjugates thereof, and methods of use CORNELL UNIVERSITY (US) 2017-04-25 US disclosed
EP-2970210-B1 PYRAZOLYLBENZO[D]IMIDAZOLE DERIVATIVES Celon Pharma Sa (PL) 2017-01-04 EP disclosed
EP-2970210-B1 PYRAZOLYLBENZO[D]IMIDAZOLE DERIVATIVES Celon Pharma Sa (PL) 2017-01-04 EP disclosed
EP-0438557-A1 NON-LINEAR OPTICALLY ACTIVE POLYIMIDES MERCK PATENT GmbH (DE) 1991-07-31 EP disclosed
WO-1991003002-A1 PHOTO-CROSSLINKED POLYMERS FOR NON-LINEAR OPTICS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-03-07 WO disclosed
WO-1991003001-A1 NON-LINEAR OPTICALLY ACTIVE POLYIMIDES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-03-07 WO disclosed
EP-0411103-A1 NON-LINEAR OPTICAL MATERIALS WITH VICINAL DONOR OR ACCEPTOR GROUPS MERCK PATENT GmbH (DE) 1991-02-06 EP disclosed
WO-1990009616-A1 NON-LINEAR OPTICAL MATERIALS WITH VICINAL DONOR OR ACCEPTOR GROUPS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-08-23 WO disclosed
US-4758312-A Adding colorless electrochemically active compound having positive reduction potential NALCO CHEMICAL COMPANY (US) 1988-07-19 US disclosed
EP-0237738-A2 Method for in situ corrosion detection using electrochemically active compounds NALCO CHEMICAL COMPANY (US) 1987-09-23 EP disclosed
US-4683035-A Method for in situ corrosion detection using electrochemically active compounds NALCO CHEMICAL COMPANY (US) 1987-07-28 US disclosed
US-4436751-A Nitrobenzyl monates antibacterial compounds BEECHAM GROUP LIMITED (GB) 1984-03-13 US disclosed
EP-0055616-A1 Antibacterial compounds BEECHAM GROUP PLC (GB) 1982-07-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250074944-A1 ACYLATED tRNA, INTRODUCTION OF PHARMACOLOGICALLY ACTIVE MOTIF IN PEPTIDE USING RIBOSOME CATALYSIS AND METHOD OF PREPARING SAME NSUN3, RNGTT, TRMT1 MAPT 3765/4885ALDH1A1 4250/4885TSHR 1367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.