Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6953425 | 0.78 | KDM4E (0.42) | ALDH1A1MAPTHTTLMNAKMT2A | |
| SCHEMBL29277536 | 0.77 | HTR6 (0.43) | ALDH1A1MAPTHTTLMNAL3MBTL1 | |
| SCHEMBL1599381 | 0.69 | KMT2A (0.57) | ALDH1A1MAPTHTTLMNAL3MBTL1 | |
| SCHEMBL13184195 | 0.69 | KMT2A (0.48) | ALDH1A1MAPTHTTLMNAL3MBTL1 | |
| SCHEMBL2066547 | 0.69 | HTT (0.53) | ALDH1A1MAPTHTTLMNAL3MBTL1 | |
| SCHEMBL9626271 | 0.69 | HTR6 (0.47) | ALDH1A1MAPTHTTLMNAL3MBTL1 | |
| SCHEMBL15232696 | 0.67 | HTR6 (0.54) | ALDH1A1MAPTHTTKMT2AMEN1 | |
| SCHEMBL7608641 | 0.67 | ALDH1A1 (0.57) | ALDH1A1MAPTHTTLMNAL3MBTL1 | |
| SCHEMBL27434278 | 0.66 | KMT2A (0.49) | ALDH1A1MAPTHTTLMNAL3MBTL1 | |
| (Phenylsulfonyl)Benzene SCHEMBL28185629 | 0.65 | HTR6 (0.64) | ALDH1A1MAPTHTTLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0931790-B1 | Method for producing 2-sulfonylpyridine derivates and method for producing 2-( (2-pyridyl)methyl)thio)-1H-benzimidazole derivates | KURARAY CO (JP) | 2003-05-14 | — | — | EP | disclosed |
| US-6350876-B2 | REACTING SULFONYL CYANIDE DERIVATIVE WITH ALPHA,BETA-UNSAT-URATED CARBONYL COMPOUND; ORGANOLITHIUM COMPOUND; STARTING MATERIAL/INTERMEDIATE FOR DRUG SYNTHESIS (ANTI-PARKINSON'S DRUG LAZABEMIDE) AND AGRICULTURAL CHEMICALS (PESTICIDES) | KURARAY CO., LTD. (JP) | 2002-02-26 | — | — | US | disclosed |
| US-20010051726-A1 | Method for producing 2-sulfonylpyridine derivatives and method for producing 2- { [ (2-pyridyl) methyl] thio} -1H-benzimidazole derivatives | KURARAY CO., LTD. (JP) | 2001-12-13 | — | — | US | disclosed |
| US-6197962-B1 | REACTING A,B-UNSATURATED CARBONYL COMPOUND WITH A SULFONYL CYANIDE; CYCLIZATION | KURARAY CO., LTD. (JP) | 2001-03-06 | — | — | US | disclosed |
| EP-0931790-A2 | Method for producing 2-sulfonylpyridine derivates and method for producing 2-( (2-pyridyl)methyl)thio)-1H-benzimidazole derivates | KURARAY CO., LTD. (JP) | 1999-07-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010051726-A1 | Method for producing 2-sulfonylpyridine derivatives and method for producing 2- { [ (2-pyridyl) methyl] thio} -1H-benzimidazole derivatives | PDXK, KCNJ2, KCNJ1 | ALDH1A1 3329/4885MAPT 3021/4885HTT 1288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.