SCHEMBL7608641

SCHEMBL7608641

CS(=O)(=O)Oc1cnc(S(=O)(=O)c2ccccc2)c(Cl)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.57
MAPT P10636 3/20 0.57
HTT P42858 3/20 0.57
LMNA P02545 2/20 0.57
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 1/20 0.41
TSHR P16473 1/20 0.40
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
MCOLN3 Q8TDD5 1/20 0.39
PKM P14618 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
NPSR1 Q6W5P4 1/20 0.37
ABCB1 P08183 2/20 0.36
PIK3CA P42336 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
HTR6 P50406 2/20 0.36
FFAR2 O15552 1/20 0.36
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7605556 0.75 ALDH1A1 (0.42) ALDH1A1MAPTLMNAL3MBTL1NPSR1
SCHEMBL7672006 0.72 ALDH1A1 (1.00) ALDH1A1MAPTHTTLMNAKMT2A
SCHEMBL27843455 0.68 CYP1A2 (0.49) ALDH1A1LMNAKMT2AKDM4ECYP3A4
SCHEMBL6947637 0.67 ALDH1A1 (0.48) ALDH1A1MAPTHTTLMNAKMT2A
SCHEMBL323791 0.66 CA1 (0.58) ALDH1A1HTTLMNAKMT2ATSHR
Methane SCHEMBL18489374 0.64 CA2 (0.56) ALDH1A1LMNAKMT2AKDM4ETDP1
Hydrochloric Acid SCHEMBL27480009 0.64 CA2 (0.56) ALDH1A1LMNAKMT2AKDM4ETDP1
SCHEMBL22688923 0.64 CA2 (0.56) ALDH1A1LMNAKMT2AKDM4ETDP1
SCHEMBL27291823 0.64 CA2 (0.56) ALDH1A1MAPTLMNAKMT2AKDM4E
Fluoride SCHEMBL27262139 0.64 CA2 (0.56) ALDH1A1LMNAKMT2AKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1140847-B1 SUBSTITUTED 2-PHENYLPYRIDINES AS HERBICIDES BASF AG (DE) 2002-12-18 EP disclosed
US-6432880-B1 APPLYING TO PLANTS BASF AKTIENGESELLSCHAFT (DE) 2002-08-13 US disclosed
CN-1336918-A Substituted 2-phenylpyridines as herbicides BASF AG (DE) 2002-02-20 CN disclosed