Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6953786 | 0.93 | CRHR1 (0.54) | CRHR1 | |
| SCHEMBL6955172 | 0.92 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL5600124 | 0.76 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL28307886 | 0.72 | CRHR1 (0.56) | CRHR1 | |
| SCHEMBL6607044 | 0.70 | NQO2 (0.52) | CRHR1 | |
| SCHEMBL6618425 | 0.69 | TERT (0.39) | CRHR1 | |
| SCHEMBL5599397 | 0.68 | CRHR1 (0.93) | CRHR1 | |
| SCHEMBL5790752 | 0.68 | CRHR1 (0.62) | CRHR1 | |
| SCHEMBL5843248 | 0.68 | CRHR1 (0.53) | CRHR1 | |
| SCHEMBL6638659 | 0.68 | CRHR1 (0.48) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977737-B1 | CRF ANTAGONISTIC QUINO- AND QUINAZOLINES | JANSSEN PHARMACEUTICA NV (BE) | 2003-09-17 | — | — | EP | claimed |