Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.54 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950385 | 0.91 | LMNA (0.53) | ESR1TSHRCYP1A2CYP2C19LMNA | |
| SCHEMBL128776 | 0.84 | CA12 (0.53) | ESR1TSHRCYP1A2LMNASMN1; SMN2 | |
| SCHEMBL6497888 | 0.84 | TSHR (0.55) | ESR1TSHRCYP1A2CYP2C19LMNA | |
| SCHEMBL131778 | 0.79 | ESR1 (0.67) | ESR1TSHRCYP1A2CYP2C19LMNA | |
| SCHEMBL131719 | 0.78 | TSHR (0.60) | ESR1TSHRCYP1A2CYP2C19LMNA | |
| SCHEMBL9741655 | 0.78 | ESR1 (0.54) | ESR1TSHRCYP1A2CYP2C19LMNA | |
| SCHEMBL9058132 | 0.77 | NPC1 (0.56) | ESR1TSHRCYP1A2CYP2C19LMNA | |
| SCHEMBL4652093 | 0.77 | CYP2D6 (0.62) | ESR1TSHRCYP1A2CYP2C19LMNA | |
| SCHEMBL111861 | 0.77 | L3MBTL1 (0.64) | ESR1TSHRCYP1A2CYP2C19LMNA | |
| SCHEMBL6946559 | 0.77 | ESR1 (0.59) | ESR1TSHRCYP1A2CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936218-B1 | BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0936218-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |