Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.58 |
| ▸ | CTSL | P07711 | 5/20 | 0.51 |
| ▸ | CTSS | P25774 | 3/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.48 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.48 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19015894 | 0.91 | CTSK (0.58) | CTSKCTSLCTSSSYKCTSB | |
| SCHEMBL7904398 | 0.87 | CTSK (0.51) | CTSKCTSLCTSSSYKCTSB | |
| SCHEMBL30902868 | 0.87 | CTSK (0.51) | CTSKCTSLCTSSSYKCTSB | |
| SCHEMBL25908024 | 0.87 | MMP9 (0.53) | CTSKCTSLCTSSSYKCTSB | |
| SCHEMBL7397262 | 0.86 | CTSK (0.52) | CTSKCTSLCTSSSYKCTSB | |
| SCHEMBL7735268 | 0.86 | CTSK (0.52) | CTSKCTSLCTSSSYKCTSB | |
| SCHEMBL7408456 | 0.85 | CTSK (0.49) | CTSKCTSLCTSSSYKCTSB | |
| SCHEMBL30480137 | 0.85 | CTSK (0.60) | CTSKCTSLCTSSCTSBPSMB5 | |
| SCHEMBL13570899 | 0.85 | SYK (0.55) | CTSKCTSLCTSSSYKCTSB | |
| SCHEMBL9819558 | 0.85 | SYK (0.55) | CTSKCTSLCTSSSYKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311292-A2 | VITRONECTIN RECEPTOR ANTAGONIST PHARMACEUTICALS | Bristol-Myers Squibb Pharma Company (US) | 2003-05-21 | — | — | EP | disclosed |
| WO-2001097861-A2 | VITRONECTIN RECEPTOR ANTAGONIST PHARMACEUTICALS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-12-27 | — | — | WO | disclosed |