Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.48 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.43 |
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.41 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950648 | 0.91 | MTNR1A (0.46) | MTNR1AMTNR1BSLC9A1SLC9A5SLC9A2 | |
| SCHEMBL21626216 | 0.84 | MTNR1B (0.47) | MTNR1AMTNR1BSLC9A1SLC9A5SLC9A2 | |
| SCHEMBL6950092 | 0.79 | MTNR1A (0.44) | MTNR1AMTNR1BSLC9A1 | |
| SCHEMBL7883370 | 0.79 | HTR2A (0.44) | MTNR1AMTNR1BSLC9A1 | |
| SCHEMBL7080318 | 0.79 | MTNR1A (0.38) | MTNR1AMPO | |
| SCHEMBL28349459 | 0.78 | MTNR1B (0.44) | MTNR1AMTNR1BSLC9A1SLC9A5SLC9A2 | |
| SCHEMBL9548993 | 0.76 | MTNR1B (0.48) | MTNR1AMTNR1BSLC9A1SLC9A5SLC9A2 | |
| SCHEMBL31561748 | 0.76 | MTNR1A (0.42) | MTNR1AMTNR1BSLC9A1 | |
| SCHEMBL6948960 | 0.76 | MTNR1A (0.40) | MTNR1AMTNR1BSLC9A1 | |
| SCHEMBL293436 | 0.76 | MTNR1B (0.41) | MTNR1AMTNR1BSLC9A1SLC9A5SLC9A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901483-B1 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LTD (GB) | 2003-07-09 | — | — | EP | disclosed |
| US-5981572-A | Benzofurans and benzopyrans as chronobiological agents | GLAXO WELLCOME INC. (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0901483-A2 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LIMITED (GB) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997043272-A2 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LIMITED (GB) | 1997-11-20 | — | — | WO | disclosed |