SCHEMBL6949013

SCHEMBL6949013

NC(=O)C(Cc1ccc(OCCn2ccc3ccccc3c2=O)cc1)Oc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.47
PPARA Q07869 18/20 0.47
PPARD Q03181 5/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6956263 0.88 PPARG (0.45) PPARGPPARAPPARD
SCHEMBL6956607 0.83 HTT (0.63) PPARGPPARA
SCHEMBL6956847 0.82 NPC1 (0.67) PPARGPPARAPPARD
SCHEMBL6952622 0.82 TNF (0.44) PPARGPPARAPPARD
SCHEMBL6954580 0.82 TNF (0.41) PPARGPPARAPPARD
SCHEMBL6948727 0.80 PPARG (0.56) PPARGPPARAPPARD
SCHEMBL6954585 0.79 TNF (0.41) PPARGPPARAPPARD
SCHEMBL6952202 0.78 PPARG (0.45) PPARGPPARAPPARD
SCHEMBL6957273 0.78 PPARG (0.47) PPARGPPARAPPARD
SCHEMBL6955832 0.76 ACKR3 (0.55) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0903343-B1 Alpha-Substituted phenylpropionic acid derivative and medicine containing the same SSP CO LTD (JP) 2003-05-28 EP disclosed
EP-0903343-A1 Alpha-Substituted phenylpropionic acid derivative and medicine containing the same SSP Co., Ltd. (JP) 1999-03-24 EP disclosed