Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.47 |
| ▸ | PPARA | Q07869 | 9/20 | 0.47 |
| ▸ | PPARD | Q03181 | 3/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6952622 | 0.91 | TNF (0.44) | PPARGPPARAPPARDITGB1ITGA4 | |
| SCHEMBL6957110 | 0.84 | MAPK1 (0.62) | ITGB1ITGA4RAB9AMAPK1 | |
| SCHEMBL6952202 | 0.81 | PPARG (0.45) | PPARGPPARAPPARDTNFRAB9A | |
| SCHEMBL6948727 | 0.80 | PPARG (0.56) | PPARGPPARAPPARDTNFRAB9A | |
| SCHEMBL6949013 | 0.78 | PPARG (0.47) | PPARGPPARAPPARD | |
| SCHEMBL6954585 | 0.78 | TNF (0.41) | PPARGPPARAPPARDTNFRAB9A | |
| SCHEMBL6952264 | 0.77 | PPARG (0.48) | PPARGPPARAPPARDITGB1ITGA4 | |
| SCHEMBL6945113 | 0.77 | SMN1; SMN2 (0.63) | PPARGITGB1ITGA4RAB9AKDM4E | |
| SCHEMBL6956676 | 0.77 | ACKR3 (0.54) | PPARGPPARAITGB1ITGA4ITGB3 | |
| SCHEMBL6956263 | 0.77 | PPARG (0.45) | PPARGPPARAPPARDTNFRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |