Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | RRM1 | P23921 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | F9 | P00740 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940750 | 1.00 | ALOX5AP (0.47) | ALOX5APMRGPRX4RXRARXRBRXRG | |
| SCHEMBL6943581 | 0.78 | REN (0.47) | RRM1F10TDP1 | |
| SCHEMBL6943335 | 0.76 | CYP4F2 (0.55) | RRM1ALOX5LMNAMAPK1 | |
| SCHEMBL4642584 | 0.75 | ALOX5AP (0.55) | ALOX5APMRGPRX4RXRARXRBRXRG | |
| SCHEMBL6940748 | 0.75 | ALOX5AP (0.48) | ALOX5APMRGPRX4RXRARXRBRXRG | |
| SCHEMBL6949100 | 0.75 | ALOX5AP (0.48) | ALOX5APMRGPRX4RXRARXRBRXRG | |
| SCHEMBL6044614 | 0.75 | ALOX5AP (0.48) | ALOX5APMRGPRX4RXRARXRBRXRG | |
| SCHEMBL6044462 | 0.75 | ALOX5AP (0.48) | ALOX5APMRGPRX4RXRARXRBRXRG | |
| SCHEMBL6044456 | 0.75 | ALOX5AP (0.48) | ALOX5APMRGPRX4RXRARXRBRXRG | |
| SCHEMBL6943816 | 0.74 | KDM4E (0.38) | LMNAMAPTTDP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |