Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6949100 | 1.00 | ALOX5AP (0.48) | ALOX5APRXRARXRBRXRGMRGPRX4 | |
| SCHEMBL6044614 | 0.78 | ALOX5AP (0.48) | ALOX5APRXRARXRBRXRGMRGPRX4 | |
| SCHEMBL6044456 | 0.78 | ALOX5AP (0.48) | ALOX5APRXRARXRBRXRGMRGPRX4 | |
| SCHEMBL6044462 | 0.78 | ALOX5AP (0.48) | ALOX5APRXRARXRBRXRGMRGPRX4 | |
| SCHEMBL6943578 | 0.78 | MTNR1A (0.46) | RENMTNR1AMTNR1BAPPBCHE | |
| SCHEMBL6943329 | 0.77 | CYP4F2 (0.61) | ABCB1HTR1ADRD2BCHEFFAR1 | |
| SCHEMBL4642584 | 0.76 | ALOX5AP (0.55) | ALOX5APRXRARXRBRXRGMRGPRX4 | |
| SCHEMBL6949104 | 0.75 | ALOX5AP (0.47) | ALOX5APRXRARXRBRXRGMRGPRX4 | |
| SCHEMBL6940750 | 0.75 | ALOX5AP (0.47) | ALOX5APRXRARXRBRXRGMRGPRX4 | |
| SCHEMBL6943813 | 0.74 | REN (0.40) | TRPA1RENDRD2KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |